PRL-8-53 is a synthetic research chemical that has intrigued the nootropic community for decades. There has been only one small human study, funded by the patent holder, on the compound in over 40 years, but the results suggested that a single dose of PRL-8-53 could improve short-term memory by more than 200%

The only human study on PRL-8-53 indicates that it may significantly boost memory, particularly in older people.

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