Ethacridine lactate monohydrate Cas 6402-23-9

Specification

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Core Traits & Mechanism

• Appearance: Yellowish crystalline powder or yellow needles, soluble in water (forming a pale yellow solution) and slightly soluble in alcohol.

• Mechanism: Disrupts bacterial cell membranes and inhibits microbial enzyme activity, exerting bacteriostatic (growth-inhibiting) or bactericidal (killing) effects—especially effective against Staphylococcus aureus, Streptococcus spp., and other skin/mucosal pathogens. It has weak antifungal activity but no antiviral effects.

Key Uses

1. Topical Antiseptic: Treats skin wounds (cuts, abrasions, burns), ulcers (e.g., pressure sores), and infected dermatoses (e.g., impetigo, folliculitis) to prevent or control bacterial infection. Often used as a dilute (0.1–0.2%) aqueous solution for irrigation, cleansing, or wet dressings.

2. Mucosal Disinfection: Diluted solutions are used for vaginal irrigation (to treat bacterial vaginosis or postpartum infections) or as a mouth rinse (for gingivitis or oral ulcers—under medical guidance to avoid ingestion).

3. Obstetric/Gynecological Use: Historically used (in controlled concentrations) for cervical ripening or as an adjuvant in labor induction (due to mild uterine stimulant effects), though this application is less common today with newer agents.

4. Veterinary Medicine: Used to treat skin infections in animals (e.g., wound care for pets).

Formulations & Precautions

• Common formulations: Aqueous solutions (0.1%), powders for reconstitution, or topical creams/ointments (combined with other agents like antibiotics or anti-inflammatories).

• Safety Notes:

• Low systemic toxicity (poor skin/mucosal absorption), but concentrated solutions may irritate skin/mucous membranes (avoid eye contact).

  Prolonged use may cause local dryness or allergic contact dermatitis in sensitive individuals.

  Not for oral ingestion (may cause nausea, vomiting, or gastrointestinal irritation).

  Avoid use in deep, puncture wounds or severe infections (requires systemic antibiotics).

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Contact information

Spring Zhang

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