Tadalafil is a selective reversible inhibitor of cycloguanosine phosphate (cGMP) specific phosphodiesterase 5 (PDE5). When sexual stimulation results in the local release of nitric oxide, PDE5 is inhibited by tadalafil, which increases the level of cGMP in the penile sponge, which leads to relaxation of smooth muscle and blood flow to the penile tissue, producing erections, as in the absence of sexual stimulation.

Chinese name Tadalafil chemical formula C22H19N3O4 molecular weight 389.404 CAS number 171596-29-5 Melting point 298 to 300 ℃ boiling point 679.1 ℃ density 1.51 g/cm3 View gray crystal solid flash point 364.5 ℃ safety description S16; S36/

The basic information

Chinese name: Tadalafil

English name: Tadalafil

CAS no. : 171596-29-5

Molecular formula: C22H19N3O4

Molecular weight: 389.404

The physical and chemical properties

Density: 1.51 g/cm3

Melting point: 298-300 ℃

Boiling point: 679.1 ℃

Flash: 364.5 ℃

LogP: 1.43

Refractive index: 1.758