Dibucaine / Cinchocaine CAS: 85-79-0 Local Anesthetic Drug Powder

Descriptions:

Dibucaine is a local anesthetic of the amide type now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local anesthetics and its parenteral use is restricted to spinal anesthesia. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1006)

Dibucaine is a Standardized Chemical Allergen. The physiologic effect of dibucaine is by means of Increased Histamine Release, and Cell-mediated Immunity. The chemical classification of dibucaine is Allergens.

Basic Information:

Chemical Names: Dibucaine; Cinchocaine; Nupercaine; 85-79-0; Nupercainal; Dermacaine More...
Molecular Formula: C20H29N3O2
Molecular Weight: 343.471 g/mol
CAS: 85-79-0
Appearance: White Powder

How should I use dibucaine topical?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Do not take by mouth. Dibucaine topical is for use only on the skin. Do not use this medicine on open wounds or on sunburned, windburned, dry, chapped, or irritated skin.

Dibucaine is usually applied to the affected area 3 or 4 times daily. Follow the label directions about how much medicine to use and how often.

Before applying dibucaine, wash the skin with soap and water. Rinse thoroughly, and pat dry gently with a tissue or soft cloth.

Apply enough of the medicine to cover the entire area to be treated.

For hemorrhoids: Dibucaine ointment may be applied to the outside of the rectum. Do not place the medicine inside the rectum. Use after each bowel movement or up to 4 times per day to treat hemorrhoid pain and itching.

Wash your hands after applying this medicine.

Dibucaine topical dosing information:

Usual Adult Dose for Local Anesthesia:

Apply topically to the affected area 3 or 4 times daily after gently washing with mild soap and warm water and drying with toilet tissue or soft cloth. No more than 30 grams should be used in a 24-hour period.

The treated area may be covered with a light gauze or bandage. Occlusive bandages are not recommended.

Usual Adult Dose for Hemorrhoids:

Instill rectally each morning and evening and after each bowel movement using a rectal applicator. Additional ointment may be applied topically to anal tissues. No more than 30 grams should be used in a 24-hour period.

Usual Pediatric Dose for Local Anesthesia:

12 years or older: Apply topically to the affected area 3 or 4 times daily after gently washing with mild soap and warm water and drying with toilet tissue or soft cloth. No more than 7.5 grams should be used in a 24-hour period.

The treated area may be covered with a light gauze or bandage. Occlusive bandages are not recommended.

It is best to use no more than 1 tube of dibucaine per day (24 hours). If you use the ointment on a child, use no more than 1/4 of a tube per day.

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