17α-Hydroxyprogesterone NEW
| Price | $29 |
| Package | 1mL |
| Supply Ability: | 10g |
| Update Time: | 2026-06-02 |
Product Details
| Product Name: 17α-Hydroxyprogesterone | CAS No.: 68-96-2 |
| Purity: 99.89% | Supply Ability: 10g |
| Release date: 2026/06/02 |
Product Introduction
Bioactivity
| Name | 17α-Hydroxyprogesterone |
| Description | 17α-Hydroxyprogesterone (17-OHP) is a physiological progestin that is produced during glucocorticoid and steroid hormone synthesis and is increased during the third trimester of pregnancy. Hydroxyprogesterone binds to the cytoplasmic progesterone receptors in the reproductive system and subsequently activates progesterone receptor-mediated gene expression. |
| In vitro | 17α-Hydroxyprogesterone is an agonist of the progesterone receptor (PR) similarly to progesterone, albeit weakly in comparison[1]. It is a chemical intermediate in the biosynthesis of steroid hormones, including the androgen and estrogen sex hormones and the glucocorticoids and mineralocorticoids. |
| In vivo | 17-Hydroxyprogesterone is a potent steroid inducer of GVBD (germinal vesicle breakdown)[3]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+90% Corn oil : 5 mg/mL (15.13 mM), Solution. 10% DMSO+90% (20% SBE-β-CD in Saline) : < 5 mg/mL (15.13 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. DMSO : 40.08 mg/mL (121.29 mM), Sonication is recommended. 10% DMSO+90% Saline : < 5 mg/mL (15.13 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. Ethanol : 61 mg/mL (184.59 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : < 5 mg/mL (15.13 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. |
| Keywords | progestogenReceptor | progestogen Receptor | ProgesteroneReceptor | Progesterone Receptor | NR3C3 | Inhibitor | inhibit | EstrogenReceptor | Estrogen Receptor | ER | EndogenousMetabolite | Endogenous Metabolite | 17α-Hydroxyprogesterone | 17αHydroxyprogesterone | 17α Hydroxyprogesterone | 17alpha-Hydroxyprogesterone | 17a-Hydroxyprogesterone |
| Inhibitors Related | Sucrose | Aceglutamide | Nicotinamide riboside malate | D(+)-Raffinose pentahydrate | Guanidine hydrochloride | Malic acid | Formamide | Glycerol | Thymidine | Corn starch | Gluconate Calcium | DL-Lysine |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Nuclear Receptor Compound Library | Bioactive Compound Library | Anti-Breast Cancer Compound Library | Drug Repurposing Compound Library | Natural Product Library | NO PAINS Compound Library | Natural Product Library for HTS | FDA-Approved Drug Library | Human Endogenous Metabolite Library | Bioactive Compounds Library Max | Gut Microbial Metabolite Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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