2-Bromo-4'-hydroxyacetophenone NEW
| Price | $29 |
| Package | 1g |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: 2-Bromo-4'-hydroxyacetophenone | CAS No.: 2491-38-5 |
| Purity: 99.07% | Supply Ability: 10g |
| Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | 2-Bromo-4'-hydroxyacetophenone |
| Description | 2-Bromo-4'-hydroxyacetophenone(PTP Inhibitor I) is a cell-permeable, protein tyrosine phosphatase (PTP) inhibitor that covalently blocks the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1(ΔSH2)) with a Ki value of 43 μM and PTP1B with a Ki value of 42 μM [1]. SHP-1 and PTP1B both have known roles in regulating insulin signaling as well as myeloid and lymphoid cell differentiation, making inhibitors of these phosphatases of interest in diabetes, cancer, allergy, and inflammation research [2]. |
| Cell Research | Cell lines: human B cells. Concentrations: 30, 100, 300, 1000 μM. Method: After incubation with varying concentrations of PTP Inhibitor I for 3 min, the cells are lysed, and the cellular proteins are separated on an SDS-PAGE gel, followed by western blot analysis. |
| Storage | Powder: -20°C for 3 years Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Ethanol : 20 mg/mL (93.01 mM), Sonication is recommended. H2O : Insoluble 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (9.3 mM), Sonication is recommended. DMSO : 60 mg/mL (279.02 mM), Sonication is recommended. |
| Keywords | protein tyrosine phosphatase(PTP) | Phosphatase | Inhibitor | inhibit | alpha-Bromo-4-hydroxyacetophenone | a-Bromo-4-hydroxyacetophenone | 4-Hydroxyphenacyl Bromide | 2Bromo4'hydroxyacetophenone | 2-Bromo-4'-hydroxyacetophenone | 2 Bromo 4' hydroxyacetophenone |
| Inhibitors Related | β-Glycerophosphate disodium salt pentahydrate | Hexane-1,6-diol | 2-[dodecyl(2-hydroxyethyl)amino]ethanol | Idoxuridine | Cyclosporine | Tartaric acid disodium dihydrate | Stearic acid | CaMKP Inhibitor | L-Ascorbic acid 2-phosphate magnesium | Cyclosporin A | L-Ascorbic acid 2-phosphate | β-Glycerophosphate disodium salt hydrate |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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