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Postion:Product Catalog >Chemical Reagents>Organic reagents>Aromatic ketones>2'-Hydroxychalcone
2'-Hydroxychalcone
  • 2'-Hydroxychalcone

2'-Hydroxychalcone NEW

Price $30 $40
Package 50mg 100mg
Supply Ability: 10g
Update Time: 2026-06-02

Product Details

Product Name: 2'-Hydroxychalcone CAS No.: 1214-47-7
Purity: 98.09% Supply Ability: 10g
Release date: 2026/06/02

Product Introduction

Bioactivity

Name2'-Hydroxychalcone
Description2'-Hydroxychalcone is a drug synthesis intermediate for the synthesis of flavonoids. 2'-Hydroxychalcone loaded in nanoemulsion showed fungicidal activity against Coccidioides parapsilosis in Danio rerio model.2'-Hydroxychalcone induced cytotoxicity through oxidative stress in lipid-loaded Hepg2 cells.2'-Hydroxychalcone inhibited the induction of ICAM-1, VCAM-α, tumor necrosis factor-α, and tumor necrosis factor-alpha as determined by reverse transcription-polymerase chain reaction determined by tumor necrosis factor-alpha induces steady-state transcript levels of ICAM-1, VCAM-1, and E-selectin, and therefore may interfere with the transcription of their genes.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+90% Saline : < 10 mg/mL (44.59 mM), Lower concentrations may be soluble, but exact solubility limit is unknown.
DMSO : 250 mg/mL (1114.83 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 10 mg/mL (44.59 mM), Solution.
KeywordsVCAM1 | TNF-α | ICAM-1 | Fungal | E-selectin | 2'-Hydroxychalcone | 1(2Hydroxyphenyl)3phenyl2propenone | 1 (2 Hydroxyphenyl) 3 phenyl 2 propenone
Inhibitors RelatedCalcium Propionate | Aceglutamide | Hemin | Guanidine hydrochloride | Terbinafine hydrochloride | Hydroxychloroquine | Benzyl propionate | Ethyl linoleate | D-Psicose | Formamide | Paeonol | Alginic acid
Related Compound LibrariesNF-κB Signaling Compound Library | Flavonoid Natural Product Library | Bioactive Compound Library | Anti-Alzheimer's Disease Compound Library | Selected Plant-Sourced Compound Library | Anti-Fungal Compound Library | Natural Product Library | Natural Product Library for HTS | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Anti-infective Natural Product Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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