2,5-Dihydroxyacetophenone NEW
| Price | $29 |
| Package | 1mL |
| Supply Ability: | 10g |
| Update Time: | 2026-06-02 |
Product Details
| Product Name: 2,5-Dihydroxyacetophenone | CAS No.: 490-78-8 |
| Purity: 99.91% | Supply Ability: 10g |
| Release date: 2026/06/02 |
Product Introduction
Bioactivity
| Name | 2,5-Dihydroxyacetophenone |
| Description | 1. 2,5-Dihydroxyacetophenone (Quinacetophenone) possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone (Quinacetophenone) reatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPKs, it also can potentiate the pro-apoptotic and anti-proliferative effects of bortezomib in U266 cells. 3. 2,5-Dihydroxyacetophenone (Quinacetophenone) has anti-inflammatory activity in activated macrophages, raising the possibility that this compound has a therapeutic potential for inflammatory conditions. 4. 2,5-Dihydroxyacetophenone (Quinacetophenone) is an uncompetitive inhibitor of murine tyrosinase (K(I) 0.28mm), it strongly inhibits both melanogenesis and cellular tyrosinase activity in vitro in 3-isobutyl-1-methylxanthin-stimulated B16 mouse melanoma cells or in vivo in zebrafish and mouse models. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 262.5 mg/mL (1725.27 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 10 mg/mL (65.72 mM), Solution. Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc. : Soluble 10% DMSO+90% Saline : < 10 mg/mL (65.72 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. |
| Keywords | Tyrosinase | TNF-α | Rehmanniae | RAW264.7 | Radix | Preparata | p65 | Nuclear factor-κB | Nuclear factor-kappaB | NF-κB | NFκB | NF-kB | NFkB | mRNA | mediators | macrophages | LPS-stimulated | iNOS | Inhibitor | inhibit | inflammatory | IL-6 | Extracellular signal regulated kinases | ERK | 2,5-Dihydroxyacetophenone | 2,5Dihydroxyacetophenone | 2,5 Dihydroxyacetophenone |
| Inhibitors Related | Urea | Sodium propionate | Kojic acid | Gum arabic | Fumaric acid | 1,4-Naphthoquinone | Ethyl linoleate | D-Psicose | Oxyresveratrol | 2-Ketoglutaric acid | N,N-Dimethylacetamide | Gluconate Calcium |
| Related Compound Libraries | Polyphenolic Natural Product Library | Traditional Chinese Medicine Monomer Library | Bioactive Compound Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Natural Product Library | Inhibitor Library | Tobacco Monomer Library | Neuroprotective Compound Library | Natural Product Library for HTS | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Food as Medicine Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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