3-Hydroxykynurenine NEW
| Price | Get Latest Price |
| Package | 1removed |
| Supply Ability: | 10g |
| Update Time: | 2026-06-01 |
Product Details
| Product Name: 3-Hydroxykynurenine | CAS No.: 484-78-6 |
| Purity: 99.50% | Supply Ability: 10g |
| Release date: 2026/06/01 |
Product Introduction
Bioactivity
| Name | 3-Hydroxykynurenine |
| Description | 3-Hydroxykynurenine (3-hydroxy-DL-Kynurenine) is an active metabolite of tryptophan and inhibits yeast and rat liver aldehyde dehydrogenase by 97 and 69%. |
| In vitro | In CD3/CD28 bead-stimulated CD4+ T cells, 3-Hydroxykynurenine (0-100 μM) dose-dependently inhibits CD4+ T-cell proliferation (IC50 = 70 μM). 3-Hydroxykynurenine (0-100 μM) dose-dependently induces significant CD4+ T-cell-mediated cell[3]. |
| In vivo | In BALB/c (H2d) mice, 3-Hydroxykynurenine (560 mg/kg; i.p.) significantly prolongs graft survival whether administered between days 1 to 7, days 7 to 14, or days 1 to 14[3]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 1.4 mg/mL (6.24 mM), Sonication and heating to 60℃ are recommended. Ethanol : 2 mg/mL (8.92 mM), Sonication is recommended. DMF : 0.5 mg/mL (2.23 mM), Sonication is recommended. PBS (pH 7.2) : 0.5 mg/mL (2.23 mM), Sonication is recommended. |
| Keywords | 3-Hydroxykynurenine | 2147-61-7 |
| Inhibitors Related | Sucrose | Aceglutamide | Nicotinamide riboside malate | D(+)-Raffinose pentahydrate | Guanidine hydrochloride | Malic acid | Formamide | Glycerol | Thymidine | Corn starch | Gluconate Calcium | DL-Lysine |
| Related Compound Libraries | Bioactive Compound Library | Natural Product Library | Inhibitor Library | Natural Product Library for HTS | Human Endogenous Metabolite Compound Library Plus | Bioactive Compounds Library Max | Gut Microbial Metabolite Library | Human Metabolite Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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