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Postion:Product Catalog >Food Additives>Antioxidants>3-O-Ethyl-ascorbic acid
3-O-Ethyl-ascorbic acid
  • 3-O-Ethyl-ascorbic acid
  • 3-O-Ethyl-ascorbic acid

3-O-Ethyl-ascorbic acid NEW

Price $95 $90 $85
Package 1kg 25kg 100kg
Min. Order: 1kg
Supply Ability: 1mt
Update Time: 2026-04-21

Product Details

Product Name: 3-O-Ethyl-ascorbic acid CAS No.: 86404-04-8
EC-No.: 617-849-3 Min. Order: 1kg
Purity: 99% Supply Ability: 1mt
Release date: 2026/04/21

New generation stable vitamin C derivative · Dual-effect whitening and antioxidant


Product Overview

3-O-ETHYL ASCORBIC ACID(CAS No.:86404-04-8) It is a highly stable derivative obtained by ethylation modification of the hydroxyl group at position 3 of the vitamin C molecule. It perfectly addresses the pain points of traditional vitamin C, such as easy oxidation, discoloration, and poor transdermal absorption, and is a star ingredient listed in the Top 30 trending efficacy ingredients of 2025.


Core Advantage

Outstanding stability:

Stored in a 60℃ aqueous solution for 6 weeks, the retention rate is as high as 95.5%, far exceeding that of the original VC (<0.01%) and VC magnesium phosphate ester (70.6%).
It is resistant to light, heat, acid, alkali, salt, and air oxidation, not easy to discolor, and the formulation has a longer shelf life.

Amphiphilic permeable structure:

Amphiphilic properties, being both hydrophilic and lipophilic, retain the water solubility of certain polar hydroxyl groups while enhancing lipid solubility through ethyl modification.  

Transdermal penetration rate is about 58%, allowing it to reach the dermis and exert biological effects.  

Easily penetrates the stratum corneum, with bioavailability significantly superior to other VC derivatives.

Gentle and low-irritation:

Compared to the original VC, it is gentler on the skin and suitable for sensitive skin. 

It has a wide pH compatibility range (4.0-6.0), matching the skin's natural pH value.


Application Guide

Recommended dosage:

Regular efficacy: 0.5% ~ 2%

High-concentration potent formula: up to 3% ~ 5%

Formulation Recommendations:

Addition Temperature: Add to the system below 40℃

pH Control: 4.0 ~ 6.0 (optimal stability range)

Stabilizer: It is recommended to add 0.2% sodium citrate

Synergistic Enhancement: Can be used in combination with niacinamide, arbutin, hyaluronic acid, and other ingredients to double the whitening and anti-inflammatory effects

Applicable Dosage Forms:

 Whitening serum (high concentration addition, intensive repair)

 Lotion, cream (long-lasting moisturization, continuous brightening)

 Gel, mask (rapid penetration, emergency brightening)

 Sunscreen and after-sun repair products (dual protection with antioxidant and anti-inflammatory)


Market Outlook

According to the 2024 Beauty Web Ingredient Trends Report, the niacinamide market is approaching saturation, while the usage rate and product count of 3-O-Ethyl-ascorbic acid both increased by nearly 20% in 2023. Data from QYResearch shows that the global market size for 3-O-Ethyl-ascorbic acid in cosmetics is about $39 million in 2024, and it is expected to reach $55 million by 2031, with a compound annual growth rate of 5.3%.


3-O-Ethyl-ascorbic acid — Empower your skincare innovation with the outstanding benefits of Vitamin C in a more stable, gentler, and more efficient way!


Company Profile Introduction

SACH BIOTECH Co.,Ltd. was reorganized and established in 2023, formerly known as Hangzhou Shitai Biotech Co.,Ltd. The main body of the company is located by the beautiful West Lake of Hangzhou. The main production base is located in Shandong Province, China, and the pilot production base and laboratory are located in Henan province. After 15 years of hard work and accumulation, we now have a strong research and development team and experimental equipment, and the pilot plant can meet the requirements of different customers. The production base located in Shandong, China can meet the needs of customers for industrial scale production.

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