99% Pharmaceutical Raw Materials Corticosteroids Powder Fluticasone Propionate CAS 80474-14-2

Fluticasone Propionate Details:

Fluticasone Propionate Description:

Fluticasone propionate belongs to a class of drugs known as corticosteroids, specifically glucocorticoids, which are hormones that predominantly affect the metabolism of carbohydrates and, to a lesser extent, fat and protein. It is used to treat asthma, allergic rhinitis, nasal polyps, various skin disorders and Crohn's disease and ulcerative colitis. It is also used to treat eosinophilic esophagitis.

Fluticasone propionate is a highly selective agonist at the glucocorticoid receptor with negligible activity at androgen, estrogen, or mineralocorticoid receptor thereby producing anti-inflammatory and vasoconstriction effects. It has been shown to have a wide range of inhibitory effects on multiple cell types (e. G. Mast cell, eosinophil, neutrophil, macrophages, and lymphocytes) and mediators (e. G. Histamine, eicosanoids, leukotrienes, and cytokines) involved in inflammation. Fluticasone propionate is stated to exert a topical effect on the lungs without significant systemic effects at usual doses, due to its low systemic bioavailability.

Fluticasone Propionate Usage:

(1) Fluticasone is a steroid. It prevents the release of substances in the body that cause inflammation.
(2) Fluticasone nasal is used to treat nasal symptoms such as congestion, sneezing, and runny nose caused by seasonal or year-round allergies. Fluticasone nasal is for use in adults and children who are at least 2 years old.
(3) Fluticasone is used to treat asthma, allergic rhinitis, nasal polyps, various skin disorders and Crohn's disease and ulcerative colitis. It is also used to treat eosinophilic esophagitis

Fluticasone Propionate COA