Chemical name: VORICONAZOLE
MF: C16H14F3N5O
MW: 349.31
CAS: 137234-62-9
Appearance: White powder
Usage: antifungal drug

COA:
 

Background:

Voriconazole (vor" i kon' a zole) is a synthetic triazole and a derivative of fluconazole, which is believed to act through inhibition of the fungal 14α-ergosterol demethylase that is responsible for converting lanosterol to ergosterol, which blocks cell membrane synthesis.  Voriconazole has a broad spectrum of activity particularly against candida and aspergillus.  Voriconazole was approved for use in the United States in 2002.  Current indications include treatment of invasive aspergillosis, esophageal candidiasis and serious candidal infections.  It is also used as empiric antifungal therapy in patients with neutropenia and persistent fever as well as preventive antifungal therapy in high risk individuals.  Voriconazole is available as tablets of 50 and 200 mg, in an oral suspension (40 mg/mL) and in a parenteral formulation generically and under the brand name Vfend.  Serious fungal infections are typically treated initially with intravenous voriconazole (4 to 6 mg/kg every 12 hours) for 3 to 10 days, followed by more prolonged therapy with oral forms (20 mg every 12 hours).  Common side effects include nausea, photosensitivity, hallucinations, headache, visual disturbances and rash.

Medical uses:

Voriconazole is used to treat invasive aspergillosis andcandidiasis and fungal infections caused by Scedosporium and Fusarium species, which may occur in immunocompromised patients, including people undergoing allogeneic bone marrow transplant (BMT), who have hematologic cancers or who undergo organ transplants.

It is also used to prevent fungal infection in people as they undergo BMT.

It is also the recommended treatment for the CNS fungal infections transmitted by epidural injection of contaminated steroids.

It can be taken by mouth or given in a doctor's office or clinic by intravenous infusion.

Advantages:

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1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.

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VORICONAZOLE 137234-62-9 Pharmaceutical Raw Materials

VORICONAZOLE 137234-62-9 Pharmaceutical Intermediate

VORICONAZOLE 137234-62-9  Raw Chemical Product

VORICONAZOLE 137234-62-9 Supplier & manufactuer