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Postion:Product Catalog >4-Hydroxyderricin
4-Hydroxyderricin
  • 4-Hydroxyderricin

4-Hydroxyderricin NEW

Price $122 $298 $447
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2025-06-18

Product Details

Product Name: 4-Hydroxyderricin CAS No.: 55912-03-3
Purity: 98% Supply Ability: 10g
Release date: 2025/06/18

Product Introduction

Bioactivity

Name4-Hydroxyderricin
Description4-Hydroxyderricin, a potent and selective MAO-B inhibitor (IC50: 3.43 μM), is the main active ingredient of Angelica sinensis, which mildly inhibits dopamine β-hydroxylase (DBH) activity and possesses antidepressant activity.
In vitro4-Hydroxyderricin (100 microM) inhibited DNA synthesis in LLC cells, but it had no effect on the DNA synthesis in human umbilical vein endothelial cells (HUVECs) or on the adherence of LLC cells to HUVECs. 4-hydroxyderricin (50 mg/kg x 2/day) inhibited the reduction of the numbers of lymphocytes, CD4+, CD8+ and natural killer (NK)-T cells in the spleen of tumor-removed mice.[2]
In vivo4-Hydroxyderricin (50 mg/kg x 2/day; oral) inhibited the tumor growth in subcutaneous LLC-implanted mice and inhibited the lung metastasis and prolonged the survival time in mice after the removal of subcutaneous tumors by surgical operation.[2] 4-Hydroxyderricin (10 to 100 microM) inhibited Matrigel-induced formation of capillary-like tubes by HUVECs.[2] The weights of the spleen and thymus in mice with subcutaneously implanted LLC were maintained close to those of normal mice by orally administered 4-hydroxyderricin.[2]
Storagestore at low temperature,keep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 90.0 mg/mL (266.0 mM), Sonication is recommended.
KeywordsMAO-B | DBH | 4-Hydroxyderricin | 4Hydroxyderricin | 4 Hydroxyderricin
Inhibitors RelatedDisulfiram | Methotrexate | Hydroxyamine hydrochloride | Rotenone | Mycophenolate Mofetil | Ribavirin | Mycophenolic acid | Benzyl alcohol | Azure B | Paeonol | Isomalt | Ivosidenib
Related Compound LibrariesPolyphenolic Natural Product Library | Bioactive Compound Library | Traditional Chinese Medicine Monomer Library | Neuronal Signaling Compound Library | Rare Natural Product Library | Selected Plant-Sourced Compound Library | Miao medicine Compound Library | Inhibitor Library | Natural Product Library for HTS | Bioactive Compounds Library Max | Ancient Chinese Classical Formulas Compound Library | Food as Medicine Compound Library

Company Profile Introduction

TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds. 170+ Compound Libraries, 10000+ Noval Small Molecucles,16000+ Nature Compounds TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.

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TargetMol Chemicals Inc.

2YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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