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Postion:Product Catalog >API>Circulatory system drugs>Antihypertensive drugs>Losartan potassium
Losartan potassium
  • Losartan potassium
  • Losartan potassium
  • Losartan potassium
  • Losartan potassium
  • Losartan potassium

Losartan potassium

Price $1
Package 1UG
Min. Order: 1UG
Supply Ability: 10000000
Update Time: 2018-10-22

Product Details

Product Name: Losartan potassium CAS No.: 124750-99-8
Min. Order: 1UG Purity: 99.5%
Supply Ability: 10000000 Release date: 2018/10/22

Losartan (potassium salt)

Synonyms
  • DuP-753
  • MK 954

 

 

 

Angiotensin II is a hormone that plays an important role in regulating blood pressure.1 Elevated levels of angiotensin II are implicated in inducing and maintaining hypertension, and also in the development of atherosclerosis. Both of these effects are mediated by the angiotensin II type 1 (AT1) receptor.2 Losartan is an AT1 receptor antagonist with a Ki value of 5-20 nM.3 It has an attenuating effect on vein graft atherosclerosis in rabbits and effectively reduces arterial blood pressure in rats.4,5 In humans, losartan controls hypertension while protecting renal function.

TECHNICAL INFORMATION
Formal Name
2-butyl-4-chloro-1-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-methanol, monopotassium salt
CAS Number
124750-99-8
Synonyms
  • DuP-753
  • MK 954
Molecular Formula
C22H23ClN6O • K
Formula Weight
461.0
Purity
≥98%
Formulation
A crystalline solid
SMILES
[H]N1N=NN=C1C2=CC=CC=C2C3=CC=C(CN4C(CO)=C(Cl)N=C4CCCC)C=C3.[K+]
InChI Code
InChI=1S/C22H23ClN6O.K/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22;/h4-7,9-12,30H,2-3,8,13-14H2,1H3,(H,25,26,27,28);/q;+1
InChI Key
VSEMWXMEXIKGTA-UHFFFAOYSA-N

 

 

 

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Company Profile Introduction

Meihua Biological Technology Co.,Ltd, is a global trading company, has been focusing on developing and manufacturing of advanced fine chemical and multiple intermediates. we are all members devoted to working in the filed for seven years. Rich experience gives us great enlightenments in founding of enterprise Meihua Biological Technology Co.,Ltd ,was established on the ground in 2011, is a collection, production, assay and sales into an integrated trading company in one of professional service and exported enterprise. As a mature manufacture, we have rigorous process flow. All final products come to us only by passing HPLC or GC assay. Through 30 procedures in all, we concentrate on every one gram of quality and every one milliliter of purity to your trust. We customize organic material,biochemical reagents,fine chemicals, pharmaceutical intermediates, OLED intermediates, liquid crystal intermediates and glucosides for customers, with high quality, competitive price, professional service and reliable source, and hundreds of species to choose. Such as 4-MPD/5F-ADB/2F-DCK/BK-EBDP/FUB-AMB/ADBF and so on, and new productions including 4433-77-6(BMK)/13605-48-6(PMK)16648-44-5(Benzeneacetic Acid ) etc. Of course, we support various transportation and safe payment. We are aiming at becoming a leading manufacture and trading company in China, even global. We are looking forward to establishing long-term cooperation relationship with customers in the word. We sincerely welcome to contact with us. For more information, please visit our website at http://www.hbmeihua.cn/

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