298-46-4
| Price | $1000 |
| Package | 1KG |
| Min. Order: | 1KG |
| Supply Ability: | 2000kg |
| Update Time: | 2019-07-06 |
Product Details
| Product Name: 298-46-4 | CAS No.: Carbamazepine |
| EC-No.: 206-062-7 | Min. Order: 1KG |
| Purity: 99% | Supply Ability: 2000kg |
| Release date: 2019/07/06 |
CR65
| Carbamazepine Basic information |
| Product Name: | Carbamazepine |
| Synonyms: | Oxcarbazepine IMpurity A;CarbaMazepine (D10, 98%);CarbaMazepine (D10, 98%) 100 ug/Ml In CH3CN-D3;CarbaMazepine (D10, 98%) 100 ug/Ml In MeOH;CarbaMazepine-13C6;Carbamazepine solution ;CARBAMAZEPIN;CARBAMAZEPINE |
| CAS: | 298-46-4 |
| MF: | C15H12N2O |
| MW: | 236.27 |
| EINECS: | 206-062-7 |
| Product Categories: | Pharmaceutical raw material;TEGRETOL;Pharmaceutical;Acids and Derivatives;Heterocycles;Active Pharmaceutical Ingredients;APIs;Pharmaceutical Chemicals;Intermediates & Fine Chemicals;Pharmaceuticals;Aromatics;Isotope Labelled Compounds |
| Mol File: | 298-46-4.mol |
 |
|
| Carbamazepine Chemical Properties |
| Melting point | 189-192 °C |
| Fp | 9℃ |
| storage temp. | 2-8°C |
| solubility | 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble29mg/mL |
| form | Crystals |
| color | Almost white |
| Water Solubility | pract. insoluble |
| Merck | 14,1781 |
| CAS DataBase Reference | 298-46-4(CAS DataBase Reference) |
| NIST Chemistry Reference | Carbamazepine(298-46-4) |
| Safety Information |
| Hazard Codes | Xn,T,F |
| Risk Statements | 42/43-22-20/21/22-39/23/24/25-23/24/25-11 |
| Safety Statements | 37-24-22-36/37/39-36-45-36/37-16 |
| RTECS | HN8225000 |
| HS Code | 29339900 |
| Hazardous Substances Data | 298-46-4(Hazardous Substances Data) |
| MSDS Information |
| Provider | Language |
|---|---|
| Carbamazepine | English |
| ACROS | English |
| Carbamazepine Usage And Synthesis |
| Chemical Properties | White Solid |
| Uses | analgesic, anticonvulsant |
| Uses | Used in treatment of pain associated with trigeminal neuralgia. Anticonvulsant |
| Definition | ChEBI: A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant. |
| Uses | Carbamazepine (CBZ) is a first generation anticonvulsant and mood stabilizing compound that has been used as a therapeutic in the context of neuropathic pain, epilepsy, and affective disorders. It exerts its effects by blocking voltage-gated sodium channels (IC50 = 640 μM), making fewer of these channels available to subsequently open, which leads to decreased high-frequency repetitive firing of action potentials. The estimated IC50 values for inhibition of Nav1.7-, Nav1.3-, and Nav1.8-type channels by CBZ following prolonged inactivation have been reported as 406, 900, and 138 μM, respectively. CBZ can also inhibit L-type Ca2+ channels (IC50 = 974 μM) and has been shown to potentiate GABAA receptors (IC50 >3 mM). |
| Carbamazepine Preparation Products And Raw materials |
| Raw materials | 2-Nitrotoluene-->Iminostilbene-->2,2'-ETHYLENEDIANILINE |
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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China- Since: 2014-12-17
- Address: Zhengzhou High tech Zone, Henan Province, China
INQUIRY
楊俊青
sales@coreychem.com
sales@coreychem.com