STAUROSPORINE
| Price | $1 |
| Package | 1KG |
| Min. Order: | 1KG |
| Supply Ability: | 1T |
| Update Time: | 2019-07-06 |
Product Details
| Product Name: STAUROSPORINE | CAS No.: 62996-74-1 |
| Min. Order: 1KG | Purity: 98% |
| Supply Ability: 1T | Release date: 2019/07/06 |
CR363
| Product Name: | STAUROSPORINE |
| Synonyms: | STSP;ANTIBIOTIC M 193;ANTIBIOTIC AM-2282;[9S-(9A,10B,11B,13A)]-2,3,10,11,12,13-HEXAHYDRO-10-METHOXY-9-METHYL-11-(METHYLAMINO)-9,13-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-1M]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1-ONE;2,3,10,11,12,13-HEXAHYDRO-10R-METHOXY-9S-METHYL-11R-METHYLAMINO-9S,13R-EPOXY-1H,9H-DIINDOLO[1,2,3-GH:3',2',1'-LM]PYRROLO[3,4-J][1,7]BENZODIAZONIN-1 ONE;STAUROSPORINE FROM STREPTOMYCES SP.;STAUROSPORINE READY-MADE SOLUTION;STAUROSPORINE FROM STREPTOMYCES SP., PGE WITH 250 UG |
| CAS: | 62996-74-1 |
| MF: | C28H26N4O3 |
| MW: | 466.53 |
| EINECS: | |
| Product Categories: | All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Protein Kinase Inhibitors and Activators;Protein Kinase;Signalling;Inhibitor;antibiotic;API |
| Mol File: | 62996-74-1.mol |
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| STAUROSPORINE Chemical Properties |
| Melting point | 270°C |
| alpha | D25 +35.0° (c = 1 in methanol); D22 +56.1° (c = 0.14 in methanol) |
| RTECS | KD5084000 |
| storage temp. | 2-8°C |
| solubility | DMSO: soluble |
| Water Solubility | Soluble in DMSO or ethanol.Soluble in dimethyl sulfoxide , dimethyl formamide, ethyl acetate, hot acetone and ethanol. Slightly soluble in chloroform and methanol. Insoluble in water. |
| InChIKey | HKSZLNNOFSGOKW-WIFUGMKFSA-N |
| Safety Information |
| Hazard Codes | Xn,T,Xi |
| Risk Statements | 40-45-36/37/38-46 |
| Safety Statements | 36/37-53-36-26-45 |
| RIDADR | UN 2811 6.1 / PGII |
| WGK Germany | 2 |
| F | 8-10 |
| HazardClass | 3 |
| HS Code | 29419090 |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| STAUROSPORINE Usage And Synthesis |
| Chemical Properties | Light Yellow Solid |
| Uses | Staurosporine is an unusual indolocarbazole alkaloid produced by a range of actinomycete species. It is a potent antitumour active, inducing apoptosis in a variety of cell lines. Staurosporine is a potent inhibitor of many kinases including protein kinase C, tyrosine kinase, CDK2/cyclin A and CDK4/cyclin D. At submicromolar concentrations, staurosporine inhibits both IKKalpha and IKKbeta. |
| Uses | Staurosporine is an unusual indolocarbazole alkaloid produced by a range of actinomycete species. It is a potent antitumor active, inducing apoptosis in a variety of cell lines. Staurosporine is a potent inhibitor of many kinases including protein kinase C, tyrosine kinase, CDK2/cyclin A and CDK4/cyclin D. At submicromolar concentrations, staurosporine inhibits both IKKalpha and IKKbeta. |
| Uses | A protein Kinase C inhibitor that induces apoptosis in many cell types |
| Biological Activity | Broad spectrum protein kinase inhibitor. Enzymes inhibited include protein kinase C (IC 50 = 3 nM), protein kinase A (IC 50 = 7 nM), p 60v-src tyrosine protein kinase (IC 50 = 6 nM) and CaM kinase II (IC 50 = 20 nM). Also available as part of the Mixed Kinase Inhibitor Tocriset™ . |
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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China- Since: 2014-12-17
- Address: Zhengzhou High tech Zone, Henan Province, China
INQUIRY
楊俊青
sales@coreychem.com
sales@coreychem.com