morpholin-3-one
| Price | $1 |
| Package | 1KG |
| Min. Order: | 1KG |
| Update Time: | 2019-07-06 |
Product Details
| Product Name: morpholin-3-one | CAS No.: 109-11-5 |
| EC-No.: 203-647-9 | Min. Order: 1KG |
| Purity: 99% | Supply Ability: Customized |
| Release date: 2019/07/06 |
Product NO: SP906
| morpholin-3-one Basic information |
| Product Name: | morpholin-3-one |
| Synonyms: | Morpholin-3-on;3-Oxomorpholine;MORPHOLIN-3-ONE;3-morpholone;3-MORPHOLINONE;morpholine-3-one;3-Ketomorpholine;Morpholin-3-one ,98% |
| CAS: | 109-11-5 |
| MF: | C4H7NO2 |
| MW: | 101.1 |
| EINECS: | 203-647-9 |
| Product Categories: | Heterocycles;Heterocycles series |
| Mol File: | 109-11-5.mol |
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| morpholin-3-one Chemical Properties |
| Melting point | 103.0 to 107.0 °C |
| Boiling point | 142°C/7mmHg(lit.) |
| CAS DataBase Reference | 109-11-5(CAS DataBase Reference) |
| EPA Substance Registry System | 3-Morpholinone(109-11-5) |
| Safety Information |
| Safety Statements | 24/25 |
| MSDS Information |
| morpholin-3-one Usage And Synthesis |
| Description | 3-ketomorpholine is also known as morpholin-3-one. It is useful pharmacological intermediate. Recent studies have shown that some morpholin-3-one derivatives could effectively cause cell cycle arrest at G1 phase, increase the levels of P53 and Fas, and induce A549 cell apoptosis in lung cancer. This indicates it might be a useful tool for elucidating the molecular mechanism of lung cancer cell apoptosis and might also be potential anti-cancer drugs. Some of its derivatives have been proven to be useful for the prevention and treatment of arteriosclerosis and hypertriglyceridemia. |
| References | He, Q., et al. "Novel morpholin-3-one derivatives induced apoptosis and elevated the level of P53 and Fas in A549 lung cancer cells." Bioorganic & Medicinal Chemistry 15.11(2007): 3889. Murai, Hiromu, et al. "Morpholinone derivatives and method of use." US, US4237132. 1980. Gonzalez-garcia, Maria Rosario, and Fernandez, Maria Carmen. "Morpholinyl derivatives useful as MOGAT-2 inhibitors." (2015). |
| morpholin-3-one Preparation Products And Raw materials |
| Raw materials | Etanol-->Ethyl acetate-->PETROLEUM ETHER-->Toluene-->Sodium hydride -->Ethanolamine-->Methyl bromoacetate |
Company:
Career Henan Chemical Co facing global High-tech pharmaceutical raw materials, high value-added new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade.
Career Henan Chemical Co is adhering to the consistent good commercial reputation, to create a highly efficient, high quality of chemical research, development, production, sales and service of integrated platform, let our customers faster, better get ideal and thoughtful service.
Contacts:
Sophia Han
Tel:86 18623837961
Whatsapp:18623837961
Skype: sophia@coreychem.com
Email:Sophia@coreychem.com
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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China- Since: 2014-12-17
- Address: Zhengzhou High tech Zone, Henan Province, China
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sales@coreychem.com
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