Desloratadine
| Price | $1 |
| Package | 1KG |
| Min. Order: | 1G |
| Supply Ability: | 100KG |
| Update Time: | 2019-07-06 |
Product Details
| Product Name: Desloratadine | CAS No.: 100643-71-8 |
| Min. Order: 1G | Purity: 98% |
| Supply Ability: 100KG | Release date: 2019/07/06 |
AD68
| Desloratadine Basic information |
| Product Name: | Desloratadine |
| Synonyms: | DESLORATADINE;DESLORATIDINE;8-chloro-6,11-dihydro-11-(4-piperdinylidene)-5h-benzo[5,6]cyclohepta[1,2-b]pyridine;8-CHLORO-6,11-DIHYDRO-11-(4-PIPERIDINYLIDENE)-5H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDINE;AKOS 92131;SCH-34117;Aerius;Dis-loratadine |
| CAS: | 100643-71-8 |
| MF: | C19H19ClN2 |
| MW: | 310.82 |
| EINECS: | 1308068-626-2 |
| Product Categories: | Active Pharmaceutical Ingredients;Antihistaminic;Various Metabolites and Impurities;Intermediates & Fine Chemicals;Metabolites;Pharmaceuticals;Heterocycles;Metabolites & Impurities;API;FLUVENT;Other APIs;Inhibitors |
| Mol File: | 100643-71-8.mol |
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| Desloratadine Chemical Properties |
| Melting point | 150-151°C |
| storage temp. | 2-8°C |
| solubility | DMSO: >10mg/mL |
| Merck | 14,2922 |
| CAS DataBase Reference | 100643-71-8(CAS DataBase Reference) |
| Safety Information |
| RTECS | DE8011000 |
| MSDS Information |
| Desloratadine Usage And Synthesis |
| Description | Desloratadine is a second generation of tricyclic antihistamine. It is a H1-receptor antagonist which has anti-inflammatory activity. Its affinity to the H1 receptor is higher than most other H1-receptor antagonists. Desloratadine works by blocking a certain natural substance (histamine) which is produced during an allergic reaction. Desloratidine has a long-lasting effect and does not cause drowsiness because it does not readily enter the central nervous system. Desloratadine is used to treat nasal and non-nasal symptoms (watery eyes, runny nose, itching eyes/nose, sneezing, and itching) of seasonal allergic rhinitis. It is also used to relieve chronic itching caused by hives. |
| Chemical Properties | Beige Solid |
| Uses | A histamine H1-receptor antagonist. An active metabolite of Loratadine |
| Uses | Nonsedating-type histamine H1-receptor antagonist. An active metabolite of Loratadine. Also inhibits generation and release of inflammatory mediators from basophils and mast cells. |
| Uses | antiinflammatory |
| Uses | For the relief of symptoms of seasonal allergic rhinitis, perennial (non-seasonal) allergic rhinitis. Desloratidine is also used for the sympomatic treatment of pruritus and urticaria (hives) associated with chronic idiopathic urticaria. |
| Definition | ChEBI: Loratadine in which the ethoxycarbonyl group attached to the piperidine ring is replaced by hydrogen. The major metabolite of loratidine, desloratadine is an antihistamine which is used for the symptomatic relief of allergic conditions including rhinitis nd chronic urticaria. It does not readily enter the central nervous system, so does not cause drowsiness. |
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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China- Since: 2014-12-17
- Address: Zhengzhou High tech Zone, Henan Province, China
INQUIRY
楊俊青
sales@coreychem.com
sales@coreychem.com