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Postion:Product Catalog >Biochemical Engineering>Inhibitors>DNA damage>DNA / RNA Synthesis inhibitors>Procarbazine hydrochloride
Procarbazine hydrochloride
  • Procarbazine hydrochloride

Procarbazine hydrochloride

Price $1
Package 1KG
Min. Order: 1G
Supply Ability: 100KG
Update Time: 2019-07-06

Product Details

Product Name: Procarbazine hydrochloride CAS No.: 366-70-1
Min. Order: 1G Purity: 98%
Supply Ability: 100KG Release date: 2019/07/06

AD68

Procarbazine hydrochloride Basic information
Product Name: Procarbazine hydrochloride
Synonyms: n-(1-methylethyl)-4-((2-methylhydrazino)methyl)benzamide hydrochloride;PROCARBAZINE HCL;PROCARBAZINE HYDROCHLORIDE;1-(p-isopropylcarbamoylbenzyl)-2-methylhydrazinehydrochloride;1-methyl-2-(p-isopropylcarbamoylbenzyl)hydrazinehydrochloride;1-methyl-2-p-(isopropylcarbamyol)benzohydrazinehydrochloride;2-(p-(isopropylcarbamoyl)benzyl)-1-methylhydrazinehydrochloride;chlorhydratede1-methyl2p(isopropylcarbamoyl)benzyl-hydrazine
CAS: 366-70-1
MF: C12H20ClN3O
MW: 257.76
EINECS: 206-678-6
Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;API;Matulane
Mol File: 366-70-1.mol
Article illustration
 
Procarbazine hydrochloride Chemical Properties
Melting point  223°C
storage temp.  -20°C Freezer
solubility  DMSO: ≥18mg/mL
color  white to tan
Water Solubility  >=10 g/100 mL at 21.5 ºC
Merck  14,7758
CAS DataBase Reference 366-70-1(CAS DataBase Reference)
EPA Substance Registry System Benzamide, N-(1-methylethyl)-4-[(2-methylhydrazino) methyl]-, monohydrochloride(366-70-1)
 
Safety Information
Hazard Codes  T
Risk Statements  45-61-22-68
Safety Statements  53-36/37-45
RTECS  XS4725000
Toxicity LD50 orally in rats: 785 ±34 mg/kg (Goldenthal)
Procarbazine hydrochloride Usage And Synthesis
Chemical Properties Crystalline Solid
Uses Antineoplastic;DNA replication inhibitor
Definition ChEBI: A hydrochloride obtained by combining procarbazine with one equivalent of hydrochloric acid. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaki g of DNA strands.
General Description White to pale yellow crystalline powder with a slight odor. Acid to litmus.
Air & Water Reactions In the presence of moisture or in aqueous solution undergoes oxidation by atmospheric oxygen. Water soluble.
Reactivity Profile Procarbazine hydrochloride is very sensitive to light. Stability is highest in aqueous acid and decreases with increasing pH. Degrades rapidly in alcoholic media and more slowly in aqueous media .
Fire Hazard Flash point data for Procarbazine hydrochloride are not available; however, Procarbazine hydrochloride is probably combustible.
 

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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  • Address: Zhengzhou High tech Zone, Henan Province, China
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