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Postion:Product Catalog >API>Blood System Drugs>Antianemia Drugs>Iron-dextran
Iron-dextran
  • Iron-dextran

Iron-dextran

Price $1
Package 1KG
Min. Order: 1G
Supply Ability: 100KG
Update Time: 2019-07-06

Product Details

Product Name: Iron-dextran CAS No.: 9004-66-4
Min. Order: 1G Purity: 98%
Supply Ability: 100KG Release date: 2019/07/06

AD68

Iron-dextran Basic information
Product Name: Iron-dextran
Synonyms: a100;a100(pharmaceutical);b75;chinofer;dextranironcomplex;dextrofer75;eisendextran;fe-dextran
CAS: 9004-66-4
MF: FeH2O4S
MW: 153.92348
EINECS:  
Product Categories: API's;API
Mol File: 9004-66-4.mol
Article illustration
 
Iron-dextran Chemical Properties
form  solution
EPA Substance Registry System Iron dextran(9004-66-4)
 
Safety Information
Hazard Codes  Xn,T
Risk Statements  40-42/43-43-45
Safety Statements  23-26-36/37/39-45-36-36/37-53
WGK Germany  -
RTECS  NI2200000
Hazardous Substances Data 9004-66-4(Hazardous Substances Data)
Toxicity LD50 i.v. in mice: 2240 mg Fe/kg (Beliles)
Iron-dextran Usage And Synthesis
Description Iron dextran is a dark brown, slightly viscous liquid complex of ferric hydroxide and dextran for intravenous or intramuscular use. Iron Dextran is used for the treatment of patients with documented iron deficiency in which oral administration is unsatisfactory or impossible. It is supplied as a parenteral preparation and is used as a hematinic. (Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1292)
Iron-Dextran is for the parenteral treatment of iron-deficiency anemia in humans and baby pigs. Can be used as a reagent.
Chemical Properties Light to dark brown powder. Colloidal suspension of an iron-dextran complex in water. pH 5.2-6.5.
History The therapeutic value of colloidal iron preparations was first reported in the 1950's by London and Twigg. Numerous attempts have been made to improve these iron preparations Thus dextran ([h] 0.05) is first heated with alkali, and is then neutralized in the presence of ferric chloride solution. Studies on this product have revealed that each particle consists of a central iron core, approximately 3nm diameter, surrounded by a dextran sheath of approximately 13nm diameter. The complex is visualized as a particle formed by a protective sheath of dextran attached by terminal metasaccharinic acid units to a b-FeOOH core. A solution of this complex containing 5% iron and 20% dextran (Imferon ™ ) is suitable for intramuscular and intravenous injection for treating iron deficiency anemia. The product is currently used widely for treating anemia in new-born piglets.
The use of these preparations has been re-examined in humans and a dramatic rise in hemoglobin was reported following intravenous infusion. The solution is best administered together with glucose solutions.
Reactivity Profile Iron-dextran is unstable at a pH of 5 and decomposes at 149-158° F. Iron-dextran may be sensitive to prolonged exposure to air.
Health Hazard SYMPTOMS: The symptoms associated with exposure to Iron-dextran are headaches, vomiting, and dizziness.
Fire Hazard Iron-dextran is combustible.

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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  • Since: 2014-12-17
  • Address: Zhengzhou High tech Zone, Henan Province, China
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