Product Details
| Product Name:
TRICHOSTATIN A |
CAS No.:
58880-19-6 |
| Min. Order:
1G |
Purity:
98% |
| Supply Ability:
100KG |
Release date:
2019/07/06 |
AD68
| TRICHOSTATIN A Basic information |
| Product Name: |
TRICHOSTATIN A |
| Synonyms: |
7-[4-(DIMETHYLAMINO)PHENYL]-N-HYDROXY-4,6R-DIMETHYL-7-OXO-2E,4E-HEPTADIENAMIDE;4,6-DIMETHYL-7-[P-DIMETHYLAMINOPHENYL]-7-OXAHEPTA-2,4-DIENOHYDROXAMIC ACID;4,6-DIMETHYL-7-[P-DIMETHYLAMINOPHENYL]-7-OXOHEPTA-2,4-DIENOHYDROXAMIC ACID;7-(4-(dimethylamino)phenyl)-n-hydroxy-4,6-dimethyl-7-oxo-4-heptadienamide;TSA;TRICHOSTATIN A;TRICHOSTATIN A, STREPTOMYCES SPECIES;Trichostatin A, Streptomyces sp. |
| CAS: |
58880-19-6 |
| MF: |
C17H22N2O3 |
| MW: |
302.37 |
| EINECS: |
|
| Product Categories: |
Anti Cancer Research;Inhibitor;antibiotic;API;Inhibitors |
| Mol File: |
58880-19-6.mol |
 |
| |
| TRICHOSTATIN A Chemical Properties |
| Melting point |
140-143℃ |
| alpha |
D20.5 +62.8° ±1.1° (c = 1.007 in ethanol) |
| density |
1.139 |
| refractive index |
136 ° (C=0.3, MeOH) |
| storage temp. |
−20°C |
| solubility |
ethanol: 1 mg/mL |
| Merck |
14,9649 |
| Hazard Codes |
Xn,Xi |
| Risk Statements |
20/21/22-36/37/38-43 |
| Safety Statements |
26-36 |
| RIDADR |
NA 1993 / PGIII |
| WGK Germany |
3 |
| RTECS |
MI5215000 |
| TRICHOSTATIN A Usage And Synthesis |
| Chemical Properties |
Solid |
| Uses |
Trichostatin A is a known inhibitor of fibrosis in vitro and in vivo, and is used as an anticancer agent. Potent differentiation inducer of friend leukemic cells. |
| Uses |
Trichostatin A is a histone deacetylase inhibitor that enhances the cytotoxic efficacy of anticancer drugs that target DNA. Trichostatin A displays antifungal, antiprotozoan and antitumour activity |
| Uses |
Trichostatin A is a histone deacetylase inhibitor that enhances the cytotoxic efficacy of anticancer drugs that target DNA. Trichostatin A displays antifungal, antiprotozoan and antitumor activity |
| Biological Activity |
Selective and potent inhibitor of histone deacetylase (K i = 3.4 nM). Active in vivo . Potential anti-cancer agent. Induces accelerated dedifferentiation of primordial germ cells (PGCs) into embryonic germ (EG) cells. |
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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