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Postion:Product Catalog >Pharmaceutical intermediates>Heterocyclic compound>Pyridine compound>Bromopyridine>2-Amino-5-bromo-3-iodopyridine
2-Amino-5-bromo-3-iodopyridine
  • 2-Amino-5-bromo-3-iodopyridine
  • 2-Amino-5-bromo-3-iodopyridine
  • 2-Amino-5-bromo-3-iodopyridine
  • 2-Amino-5-bromo-3-iodopyridine

2-Amino-5-bromo-3-iodopyridine NEW

Price $15
Package 1kg
Min. Order: 1kg
Supply Ability: 10000kg/month
Update Time: 2024-05-23

Product Details

Product Name: 2-Amino-5-bromo-3-iodopyridine CAS No.: 381233-96-1
Min. Order: 1kg Purity: 99.9%
Supply Ability: 10000kg/month Release date: 2024/05/23

Chinese name: 2-amino-3-iodo-5-bromopyridine

English name: 2-AMINO-5-BROMO-3-IODOPYRIDINE

CAS: 381233-96-1

Molecular formula: C5H4BrIN2

MDL number: MFCD06659000

Molecular weight: 298.91

Melting point: 111-112°C

Boiling point: 308.2±42.0 °C(Predicted)

Density: 2.426± 0.06g /cm3(Predicted)

Storage conditions: Keep in dark place,Sealed in dry,Room Temperature

Acidity coefficient (pKa) : 2.25±0.49(Predicted)

Sensitive photosensitivity

InChIKey: XPERZSKJGNUSHI-UHFFFAOYSA-N

Apply

2-amino-3-iodo-5-bromopyridine can be used to synthesize tyrosine kinase inhibitors to treat cancer or prevent the spread of cancer cells, and CRAC inhibitors to treat autoimmune and inflammatory diseases.

preparation

Add 38ml of mixed solvent ethyl acetate and ethanol, and 15ml ethyl acetate into a 100ml round-bottom single-mouth flask. Insert a thermometer, start a magnetic stirrers, add 17.4g of 2-amino-5-bromopyridinium, add 39.38g of n-iodosuccinimide, and stir continuously at 25℃ for 18 hours. TLC and GC determined that the reaction of 2-amino-5-bromopyridine was complete. The product was recrystallized with a mixture of n-hexane and ethanol to obtain 2-amino-3-iodo-5-bromopyridine. After drying, the calculated yield was 80.3%, and the purity was 97.2%. Nuclear magnetic resonance analysis: 1HMR(CDCl3)400MHz:δ7.98 (s,1H); δ7.66(s,1H); Delta 4.96 (bs, 2 h


Company Profile Introduction

-WUHAN BOYUAN IMPORT & EXPORT CO.,LTD.. is specialized in R&D, manufacturing and marketing APIS, Food Additives,Inorganic Chemicals,Organic Intermediate,Health Care Products,Feed Additives,Chemical Reagents,Daily Chemicals etc.More than 70 percent products are exported to Europe, America, Japan and Southeast Asia. In the past years, WUHAN BOYUAN IMPORT & EXPORT CO.,LTD. has established its professional team and advanced managements, excels in product sourcing and customized products. WUHAN BOYUAN IMPORT & EXPORT CO.,LTD. has built close collaborations with several well-known institutes in China. Development of new fine chemical, custom synthesis has been a significant part of our chemical's production. The essence of our business is commitment to customer service by meeting and/or exceeding our client's expectations of cost, quality, and efficient service. We are confident that our competitive edge will provide the foundation ensure for our customers to be successful in their own market areas. Our company offers variety of products which can meet your multifarious demands. We adhere to the management principles of "quality first, customer first and credit-based" since the establishment of the company and always do our best to satisfy potential needs of our customers. Our company is sincerely willing to cooperate with enterprises from all over the world in order to realize a win-win situation since the trend of economic globalization has developed with anirresistible force

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