Irinotecan hydrochloride
| Price | $1 |
| Package | 1kg |
| Min. Order: | 1g |
| Supply Ability: | 100KG |
| Update Time: | 2019-07-06 |
Product Details
| Product Name: Irinotecan hydrochloride | CAS No.: 100286-90-6 |
| Min. Order: 1g | Purity: 99% |
| Supply Ability: 100KG | Release date: 2019/07/06 |
| Product:: AD68 |
| Irinotecan hydrochloride Basic information |
| Product Name: | Irinotecan hydrochloride |
| Synonyms: | Camptothecin II;CPT-II;[1,4′-Bipiperidine]-1′-carboxylic acid, CPT-11,(S)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl ester;(4S)-4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl[1,4'-bipiperidine]-1'-carboxylicacidesterhydrochloride;(S)-4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl ester;Irinotecan hydrochloride(CPT-11);Irinotecan HCI;Irinotecan-D10 HCl |
| CAS: | 100286-90-6 |
| MF: | C33H39ClN4O6 |
| MW: | 623.14 |
| EINECS: | 1308068-626-2 |
| Product Categories: | API;Anti-cancer&immunity;Active Pharmaceutical Ingredients;Antineoplastic;Antitumors for Research and Experimental Use;Biochemistry;Chiral Reagents;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Irinotecan |
| Mol File: | 100286-90-6.mol |
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| Irinotecan hydrochloride Chemical Properties |
| Melting point | 250-256°C (dec.) |
| Boiling point | 257 °C |
| refractive index | 67.7 ° (C=1, H2O) |
| storage temp. | Refrigerator |
| solubility | Soluble in DMSO or DMF at approximately 20mg/ml. Sparingly soluble in aqueous buffers. /n |
| Water Solubility | Soluble in DMSO at 100mg/ml. Soluble in water at 25mg/ml with warming |
| Merck | 5091 |
| CAS DataBase Reference | 100286-90-6(CAS DataBase Reference) |
| Safety Information |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| RTECS | DW1060750 |
| MSDS Information |
| Irinotecan hydrochloride Usage And Synthesis |
| Chemical Properties | Yellow Crystalline Powder |
| Uses | antineoplactic;'inhibitor of topoisomerase I |
| Uses | A DNA topoisomerase inhibitor |
| Definition | ChEBI: A hydrochloride obtained by combining irinotecan with one molar equivalent of hydrochloric acid. Used (in the form of its trihydrate) in combination with fluorouracil and leucovorin, for the treatment of patients with metastatic adenocarcinoma of the pancr as after disease progression following gemcitabine-based therapy. It is converted via hydrolysis of the carbamate linkage to its active metabolite, SN-38, which is ~1000 times more active. |
| Brand name | Camptosar (Pharmacia &Upjohn) . |
| Biological Activity | Inhibitor of DNA topoisomerase I that displays antitumor activity against a range of tumor types. |
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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China- Since: 2014-12-17
- Address: Zhengzhou High tech Zone, Henan Province, China
INQUIRY
楊俊青
sales@coreychem.com
sales@coreychem.com