XL518
| Price | $2 |
| Package | 1kg |
| Min. Order: | 1kg |
| Supply Ability: | 100kg |
| Update Time: | 2019-07-06 |
Product Details
| Product Name: XL518 | CAS No.: 934660-93-2 |
| Min. Order: 1kg | Purity: 99% |
| Supply Ability: 100kg | Release date: 2019/07/06 |
| Product Number:: WM.819 |
| XL518 Basic information |
| Product Name: | XL518 |
| Synonyms: | XL518;GDC-0973;RG7420;[3,4-difluoro-2-[(2-fluoro-4-iodophenyl)aMino]phenyl][3-hydroxy-3-[(2S)-2-piperidinyl]-1-azetidinyl]Methanone;GDC-0973(XL-518);(S)-(3,4-difluoro-2-(2-fluoro-4-iodophenylaMino)phenyl)(3-hydroxy-3-(piperidin-2-yl)azetidin-1-yl)Methanone;XL518 ,GDC-0973;CobiMetinib |
| CAS: | 934660-93-2 |
| MF: | C21H21F3IN3O2 |
| MW: | 531.3100196 |
| EINECS: | |
| Product Categories: | Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Protein Kinase Inhibitors and Activators;API;MAPK |
| Mol File: | 934660-93-2.mol |
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| XL518 Chemical Properties |
| density | 1.706 |
| Safety Information |
| MSDS Information |
| XL518 Usage And Synthesis |
| Uses | A potent, selective, orally bioavailable inhibitor of MEK1, a component of the RAS/RAF/MEK/ERK pathway. It inhibits proliferation and stimulates apoptosis in a variety of human tumor cell lines. In preclinical xenograft models, oral administration of XL518 results in sustained inhibition of pERK in tumor tissue, but not brain tissue, leading to tumor growth inhibition and regression at well tolerated doses. |
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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China- Since: 2014-12-17
- Address: Zhengzhou High tech Zone, Henan Province, China
INQUIRY
楊俊青
sales@coreychem.com
sales@coreychem.com