6-Hydroxyflavanone NEW
| Price | Get Latest Price |
| Package | 1removed |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: 6-Hydroxyflavanone | CAS No.: 4250-77-5 |
| Purity: 99.85% | Supply Ability: 10g |
| Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | 6-Hydroxyflavanone |
| Description | 6-Hydroxyflavanone, extracted from the leaves of Acorus calamus, exhibits anti-inflammatory and anti-neuropathic pain activity by targeting cyclooxygenase-2 (COX-2), 5-lipoxygenase (5-LOX), as well as opioid and GABA-A receptors. 6-Hydroxyflavanone has anti-injury sensory properties in a streptozotocin-induced diabetic neuropathy model. in a streptozotocin-induced diabetic neuropathy model with anti-injury sensory properties. |
| In vivo | 6-Hydroxyflavanone (6-HF) (6-HF) (5, 30, and 60 mg/kg ) inhibited the COX-2 and 5-LOX enzymes significantly. It substantially reduced heat nociception in a hot plate analgesia meter, as well as carrageenan-induced paw edema in rodent models. The authors discovered that 6-HF exhibited anti-nociception properties in a streptozotocin-induced diabetic neuropathy (DIN) model. According to the findings of this study, 6-HF demonstrated the ability to diminish inflammation caused by diabetes, as well as to exert an anti-nociceptive.[3] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 2.41 mg/mL (10.03 mM), Sonication is recommended. |
| Keywords | GABAReceptor | GABAA | GABA Receptor | COX-2 | 6-Hydroxyflavanone | 6Hydroxyflavanone | 6 Hydroxyflavanone | 5-LOX |
| Inhibitors Related | Caffeic Acid | p-Hydroxybenzaldehyde | Acetaminophen | Urethane | Phenidone | Penicillin G sodium salt | Valproic Acid | Indomethacin | Methyl eugenol | Trometamol | 5-Methylfurfural | Magnesium sulfate |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Flavonoid Natural Product Library | Bioactive Compound Library | Pain-Related Compound Library | Traditional Chinese Medicine Monomer Library | Membrane Protein-targeted Compound Library | Selected Plant-Sourced Compound Library | Natural Product Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Natural Product Library for HTS | Anti-Aging Compound Library | Bioactive Compounds Library Max |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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