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Postion:Product Catalog >API>Antineoplastic agents>Tinib Antineoplastic drugs>Mubritinib
Mubritinib
  • Mubritinib

Mubritinib

Price $3
Package 3KG
Min. Order: 1KG
Supply Ability: 100kg
Update Time: 2019-08-08

Product Details

Product Name: Mubritinib CAS No.: 366017-09-6
Min. Order: 1KG Purity: 99%
Supply Ability: 100kg Release date: 2019/08/08
Product Model: windy
Mubritinib Basic information
Product Name:
Mubritinib
Synonyms:
(E)-1-(4-(4-((2-(4-(trifluoromethyl)styryl)oxazol-4-yl)methoxy)phenyl)butyl)-1H-1,2,3-triazole;1-(4-(4-((2-((1E)-2-(4-(Trifluoromethyl)phenyl)ethenyl)-4-oxazolyl)methoxy)phenyl)butyl)-1H-1,2,3-triazole Mubritinib (TAK 165);MUBRITINIB;1-(4-(4-((2-((1E)-2-(4-(Trifluoromethyl)phenyl)ethenyl)-4-oxazolyl)methoxy)phenyl)butyl)-1H-1,2,3-triazole;Mubritinib 1-(4-(4-((2-((1E)-2-(4-(Trifluoromethyl)phenyl)ethenyl)-4-oxazolyl)methoxy)phenyl)butyl)-1H-1,2,3-triazole;(E)-4-((4-(4-(1H-1,2,3-Triazol-1-yl)butyl)phenoxy)methyl)-2-(4-(trifluoromethyl)styryl)oxazole;TAK 165;Mubritinib(TAK 165)
CAS:
366017-09-6
MF:
C25H23F3N4O2
MW:
468.47
EINECS:
 
Product Categories:
Inhibitors
Mol File:
366017-09-6.mol
Article illustration
 
Mubritinib Chemical Properties
Melting point 
158.0 to 162.0 °C
storage temp. 
Store at +4°C
 
Safety Information
MSDS Information
 
 
Mubritinib Usage And Synthesis
Uses
Treatment of cancer.
Biological Activity
Potent, irreversible human epithelial growth factor receptor 2 (ErbB2) inhibitor (IC 50 = 6 nM) that displays > 4000-fold selectivity over EGFR, FGFR, PDGFR, JAK1 and Src. Exhibits potent antiproliferative effects in ErbB2-overexpressing cancer cell lines (IC 50 = 5 nM in BT474 breast cancer cells) and significantly inhibits bladder, breast and prostate cancer xenograft growth in vivo .

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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