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Postion:Product Catalog >Biochemical Engineering>Inhibitors>PI3K / Akt / mTOR>mTOR inhibitors> Ridaforolimus
	Ridaforolimus
  • 	Ridaforolimus

Ridaforolimus

Price $7
Package 1KG
Min. Order: 1KG
Update Time: 2019-09-02

Product Details

Product Name: Ridaforolimus CAS No.: 572924-54-0
Min. Order: 1KG Purity: 99%
Supply Ability: JD 427 Release date: 2019/09/02
Product Name:
Ridaforolimus
Synonyms:
AP 23573, MK 8669, 42-DiMethylphosphinate-rapaMycin;RapaMycin,42-(diMethylphosphinate) (9CI);deforolimus 572924-54-0;572924-54-0;Deforolimus (AP23573)42-;Deforolimus, 98%, a potent and selective mTOR inhibitor;42-(Dimethylphosphinate)rapamycin;Deforolimus
CAS:
572924-54-0
MF:
C53H84NO14P
MW:
990.214
EINECS:
 
Product Categories:
Inhibitors;Akt;Intermediates & Fine Chemicals;Pharmaceuticals;mTOR;PI3K
Mol File:
572924-54-0.mol
Article illustration
 
Ridaforolimus Chemical Properties
Melting point 
95-98°C
storage temp. 
Hygroscopic, -20?C Freezer, Under Inert Atmosphere
 
Safety Information
MSDS Information
 
 
Ridaforolimus Usage And Synthesis
Chemical Properties
Off-White Solid
Uses
An immunosupressant and is currently being investigated for use in cancer treatments. Ridaforolimus may act as a regulator of protein synthesis, cell proliferation, cell cycle progression and cell survival. Ridaforolimus, was formerly known as Deforolimus.
Uses
Ridaforolimus is a semisynthetic macrocyclic lactone prepared from rapamycin by selective alkylation of the 42-hydroxy group with a dimethylphosphinate moiety. Like all tacrolimus analogues, ridaforolimus binds to receptor protein, FKBP12. The complex then binds to mTOR preventing its interaction with target proteins. Ridaforolimus is extensively cited in the literature with over 70 citations.
Definition
ChEBI: A semisynthetic derivative that is sirolimus in which hydroxy group attached to the cyclohexyl moiety has been converted to the corresponding dimethylphosphinate.

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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