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Postion:Product Catalog >API>Antibiotics>Polyenes drug>Nystatin
Nystatin
  • Nystatin
  • Nystatin

Nystatin

Price $2
Package 25Kg/Drum
Min. Order: 25Kg/Drum
Supply Ability: 1ton
Update Time: 2019-10-29

Product Details

Product Name: Nystatin CAS No.: 1400-61-9
Min. Order: 25Kg/Drum Purity: 99%
Supply Ability: 1ton Release date: 2019/10/29

Product Name: Nystatin

Specification: 99%

Cas No: 1400-61-9

Einecs No: 215-749-0

Molecular formula: C47H75NO17

Molecular weight: 926.10

 

Nystatin is an antifungal medication. It is used to treat Candida infections of the skin including diaper rash, thrush, esophageal candidiasis, and vaginal yeast infections. It may also be used to prevent candidiasis in those who are at high risk. Nystatin may be used by mouth, in the vagina, or applied to the skin.

Like amphotericin B and natamycin, nystatin binds to ergosterol, a major component of the fungal cell membrane. When present in sufficient concentrations, it forms pores in the membrane that lead to K+ leakage and death of the fungus. Ergosterol is fairly unique to fungi, so the drug does not have such catastrophic effects on animals.

 

 

Test items

Standard

Result

Description

Yellow   brown powder

Conforms

 

Identification

IR

IR spectrum of sample is the same as working standard

Conforms

HPLC

HPLC RT of the sample is the same as the working standard

Conforms

Melting point

165.0°C~169.0°C

165.8°C~167.0°C

Optical rotation

-23°~-29°

-27.4°

Loss on drying

NMT 1.0 %

0.17%

Residue on ignition

NMT 0.1 %

0.03%

Heavy metals

NMT 20ppm

Conforms

Related substances

Impurity A

NMT 0.1 %

Not detected

Impurity B

NMT 0.1 %

Not detected

Impurity C

NMT 0.1 %

0.02%

Single impurity

NMT 0.2 %

0.17%

Total impurity

NMT 1.0 %

0.60%

Assay

NLT 99.0%

99.0%

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