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Postion:Product Catalog >API>Antibiotics>β-Lactamase inhibitors>Side chain for meropenem
Side chain for meropenem
  • Side chain for meropenem
  • Side chain for meropenem

Side chain for meropenem

Price $1
Package 25Kg/Drum
Min. Order: 25Kg/Drum
Supply Ability: 1ton
Update Time: 2019-10-30

Product Details

Product Name: Side chain for meropenem CAS No.: 96034-64-9
Min. Order: 25Kg/Drum Purity: 99%
Supply Ability: 1ton Release date: 2019/10/30

Introduction                                            

English name: 
Meropenem   
Synonyms:

4r,5s,6s)-3-[[(3s,5s)-5-dimethylcarbamoylpyrrolidin-3-;(4r,5s,6s)

-3-[[(3s,5s)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]thio]-6-[(1r)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2

-carboxylic acid;)-3-pyrrolidinyl)thio)-6-(1-hydroxyethyl)-4-methyl

-7-oxo-,(4r-(3(s*,5s*),4-al;5-beta,6-beta(r*)))-ph;

CAS NO.:
96036-03-2
Appearance: 
white crystalline powder
Molecular weight: 
383.46
Molecular formula:

C17H25N3O5S  

Function: 
Antinfective 

 

 

Meropenem is an ultra-broad spectrum injectable antibiotic used to treat a wide variety of infections, including meningitis and pneumonia. It is a beta-lactam and belongs to the subgroup of carbapenem, similar to imipenem and ertapenem.

Function                                                  

 The spectrum of action includes many Gram-positive and Gram-negative bacteria (including Pseudomonas) and anaerobic bacteria. The overall spectrum is similar to that of imipenem, although meropenem is more active againstEnterobacteriaceae and less active against Gram-positive bacteria. It is also very resistant to extended-spectrum beta lactamases but may be more susceptible to metallo-beta-lactamases. Meropenem is frequently given in the treatment of febrile neutropenia. This condition frequently occurs in patients withhematological malignancies and cancer patients receiving anticancer drugs that cause bone marrow suppression. It is approved for complicated skin and skin structure infections, complicated intra-abdominal infections and bacterial meningitis.

 

Specification                                          

 

Items

Specification

Results

Appearance

White or off-white powder

Conformed

Identification

Meets the requirements

Conformed

pH

7.3-8.3

8.07

Loss on drying

9.0%~12.0%

10.2%

Chromatographic

RRT(0.45)

0.80% MAX

0.13%

purity

RRT(1.90)

0.60% MAX

0.15%

Particulate matter

≥10 um

≤6000 pc/g

Conformed

≥25 um

≤600 pc/g

Conformed

Uniformity of dosage unites

Meets the requirements

conformed

Bacterial endotoxinsunder

≤0.125EU/mg

Conformed

Sterility

Meets the requirements

Conformed

Content of sodium

5.3%-8.0%

6.8%

Assay(C17H25N3O5S) on anhydrous basis

≥ 76.0%

80.7%

Conclusion

The product conforms the USP30 standard

Packing storage

In tight containers, the dry powder at controlled room temperature

 

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