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Postion:Product Catalog >Organic Chemistry>Ketones>6PPD-Q
6PPD-Q
  • 6PPD-Q

6PPD-Q NEW

Price $55 $125 $183
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: 6PPD-Q CAS No.: 2754428-18-5
Purity: 99.20% Supply Ability: 10g
Release date: 2026/05/11

Product Introduction

Bioactivity

Name6PPD-Q
Description6PPD-Q (6PPD-Quinone) is an environmental pollutant that can target CNR2, CNR1, AA2AR, LCAT and TRPA1. Among them, CNR2 has the highest binding affinity and may act as a CNR2 receptor agonist to activate cannabinoid receptors. 6PPD-Q can damage the sperm quality and induce the impairment of male reproductive ability in mice. 6PPD-Q can induce intestinal inflammation and barrier damage by disrupting mitochondrial function, reducing neuronal glycolytic metabolites and TCA cycle intermediates, and exacerbating α-synuclein (α-syn) aggregation.
In vitroMETHODS: Mouse dopaminergic neurons were treated with 6PPD-Q (10 nM, 100 nM) for 48 hours to detect cell growth inhibition. RESULTS: R6PPD-Q did not exhibit significant cytotoxicity. [1] METHODS: Mouse dopaminergic neurons were treated with 6PPD-Q (10 nM, 100 nM) for 7 days, and target protein expression was detected by Western Blot. RESULTS: R6PPD-Q significantly increased Triton X-100-insoluble α-synuclein (α-syn) protein levels. [1]
In vivoMETHODS: To study the effect of 6PPD-Q on intestinal injury, 6PPD-Q (0.1, 1, 10, 100 μg/kg) was orally administered to ICR mice once daily for 21 days. RESULTS: 6PPD-Q caused intestinal injury in ICR mice, which was manifested as enhanced inflammatory response in jejunum and ileum and impaired intestinal barrier integrity. [2]
StorageKeep away from direct sunlight,Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 10 mg/mL (33.51 mM), Sonication and heating are recommended.
H2O : < 1 mg/mL (insoluble or slightly soluble)
KeywordsEndogenousMetabolite | Endogenous Metabolite | 6PPD-Q
Inhibitors RelatedSucrose | Aceglutamide | Nicotinamide riboside malate | D(+)-Raffinose pentahydrate | Guanidine hydrochloride | Malic acid | Formamide | Glycerol | Thymidine | Corn starch | Gluconate Calcium | DL-Lysine
Related Compound LibrariesBioactive Compound Library | Natural Product Library | Natural Product Library for HTS | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Human Metabolite Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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