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Postion:Product Catalog >6RK73
6RK73
  • 6RK73

6RK73 NEW

Price $147 $313 $537
Package 1mg 5mg 10mg
Supply Ability: 10g
Update Time: 2025-07-15

Product Details

Product Name: 6RK73 CAS No.: 1895050-66-4
Purity: 100% Supply Ability: 10g
Release date: 2025/07/15

Product Introduction

Bioactivity

Name6RK73
Description6RK73 is a covalent, irreversible, and specific UCHL1 inhibitor (IC50: 0.23 μM) with almost no inhibition of UCHL3 (IC50: 236 μM).
Cell ResearchCell Line: MDA-MB-436 cells Concentration: 5 μM Incubation Time: 24, 48 hours
In vitro6RK73 (5 μM; 1-3 hours) treatment displays strong inhibition of the TGFβ-induced pSMAD2 and pSMAD3, and a decrease of TβRI and total SMAD protein levels in MDA-MB-436 cells. 6RK73 (5 μM; 24-48 hours) results in migration significantly slower than the DMSO control group in MDA-MB-436 cells[1].
In vivo6RK73 displays a potent inhibition of breast cancer extravasation in zebrafish[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility InformationDMSO : 112.5 mg/mL (366 mM), Sonication is recommended.
Keywords6RK-73 | 6RK73
Related Compound LibrariesBioactive Compound Library | Anti-Breast Cancer Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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4YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, USA
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