一二三四区视频,亚洲少妇熟女色,日本久热无码视频网,欧美国产日韩大尺度,亚洲a视频,久久少妇一区二区,日韩999无码视频,刺激久久久久久久,啊啊啊啊不要啊在线

Welcome to chemicalbook!
+1 (818) 612-2111
RFQ
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

RFQ
skype
MY Account
Top
Postion:Product Catalog >7-Nitroindazole
7-Nitroindazole
  • 7-Nitroindazole

7-Nitroindazole NEW

Price $29
Package 200mg
Supply Ability: 10g
Update Time: 2026-06-01

Product Details

Product Name: 7-Nitroindazole CAS No.: 2942-42-9
Purity: 99.05% Supply Ability: 10g
Release date: 2026/06/01

Product Introduction

Bioactivity

Name7-Nitroindazole
Description7-Nitroindazole is a non-selective inhibitor of NOS isoforms in vitro for neuronal nitric oxide synthase showing a 10-fold selectivity for neuronal NOS.
Animal ResearchAnimals were divided into four groups (n = 12) as follows:group 1: control animals, treated with saline for 7 days, which were involved in the experiment from the very beginning and housed under the same standard laboratory conditions as the treated animals;group 2: animals, receiving 15 mg/kg?1 i.p. of cocaine for 7 days;group 3: animals, receiving 25 mg/kg?1 i.p. 7-NI for 7 days ;group 4: animals, treated with 7-NI (25 mg/kg?1 i.p.) and 30 min later with cocaine (15 mg/kg?1) for 7 days.Twenty-four hours after the last administration of the compounds the animals were observed for behavioral changes related to the withdrawal syndrome.?Then the animals were sacrificed through decapitation and brains were extracted.?Brains of six animals from each group were taken for isolation of synaptosomes and brains from the other six animals of each group were used for measurement of nNOS and antioxidant enzymes[1].
In vivoIn the experimental model of cocaine multiple administration in rats the selective nNOS inhibitor 7-nitroindazole not only attenuated the behavioral changes induced by cocaine deprivation but also exerted an antioxidant and neuroprotective activity.?The possible mechanisms underlying the neuroprotective effects of 7-NI could be due to the combination of its inhibitory effect of nNOS and its direct free radical scavenging properties.?The beneficial effect of 7-NI in restoration of the antioxidant cell defense in the brain, impaired by multiple cocaine administration, and along with it the attenuation of the physical dependence, induced by cocaine, once again confirm the role of the oxidative stress in the development of addiction to psychoactive compounds[1].
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+40% PEG300+5% Tween 80+45% Saline : 10 mg/mL (61.3 mM), Solution.
DMSO : 250 mg/mL (1532.52 mM), Sonication is recommended.
10% DMSO+90% Saline : < 10 mg/mL (61.3 mM), Lower concentrations may be soluble, but exact solubility limit is unknown.
KeywordsNOS | NO Synthase | Nitric oxide synthases | Inhibitor | inhibit | 7-Nitroindazole | 7Nitroindazole | 7 Nitroindazole
Inhibitors Related2-Isopropyl-1H-imidazole | Chondroitin sulfate | L-NAME hydrochloride | Mifepristone | Aminopicoline | Agmatine sulfate | 3-AMINO-1,2,4-TRIAZINE | Nitroarginine | Methylene Blue trihydrate | Gluconate Calcium | Diallyl disulfide | Magnesium sulfate
Related Compound LibrariesNonsteroidal Anti-Inflammatory Compound Library | Bioactive Compound Library | Anti-Viral Compound Library | Inhibitor Library | NO PAINS Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Human Metabolite Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

You may like

Recommended supplier

Product name Price   Suppliers Update time
$76.00
VIP4Y
TargetMol Chemicals Inc.
2026-04-20
VIP6Y
WUHAN FORTUNA CHEMICAL CO., LTD
2021-06-04
VIP5Y
Shanghai Joiny Pharmaceutical Co.,LTD
2023-02-14
$15.00
Zhuozhou Wenxi import and Export Co., Ltd
2021-06-27
$6.68
VIP7Y
Career Henan Chemical Co
2020-01-09

TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
INQUIRY
临武县| 河曲县| 井冈山市| 新宁县| 石楼县| 邓州市| 友谊县| 桂平市| 甘南县| 海安县| 布拖县| 昆明市| 泸水县| 虎林市| 泰和县| 遂昌县| 崇明县| 新乐市| 博野县| 富宁县| 惠东县| 铜陵市| 永新县| 体育| 渑池县| 德化县| 永善县| 天峨县| 京山县| 海晏县| 潮安县| 仙居县| 英吉沙县| 莲花县| 太原市| 丹寨县| 大洼县| 安徽省| 板桥市| 伊春市| 珲春市|