Teprenone
| Price | $1 |
| Package | 1KG |
| Min. Order: | 1KG |
| Supply Ability: | 1ton |
| Update Time: | 2019-12-20 |
Product Details
| Product Name: Teprenone | CAS No.: 6809-52-5 |
| EC-No.: 200-110-4 | Min. Order: 1KG |
| Purity: 95%~99% | Supply Ability: 1ton |
| Release date: 2019/12/20 | |
| Contact email address: Flora@coreychem.com |
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Teprenone Basic information
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Product Name:
Teprenone
Synonyms:
All trans-Teprenone;6,10,14,18-Tetramethyl-5,9,13,17-nonadecatetraen-2-one, mixture of (5E,9E,13E) and (5Z,9E,13E) isomers;6,10,14,18-tetramethyl-5,9,13,17-nonadecatetraen-2-one;UNII-S8S8451A4O;Teprenone, >=98%;Teprenone (trans,trans);TEPRENONE;13,17-nonadecatetraen-2-one,6,10,14,18-tetramethyl-9
CAS:
6809-52-5
MF:
C46H76O2
MW:
661.09
EINECS:
614-276-0
Product Categories:
Aliphatics;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:
6809-52-5.mol
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Teprenone Chemical Properties
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Boiling point
bp0.01 155-160°
density
d420.5 0.9081
refractive index
nD20 1.4947
storage temp.
?20°C
solubility
DMSO: >5mg/mL
form
liquid
color
clear
Merck
14,9228
InChIKey
SBOCYPUKNYDTSX-DMLVRTFPSA-N
CAS DataBase Reference
6809-52-5(CAS DataBase Reference)
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Safety Information
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WGK Germany
3
RTECS
RA5391300
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MSDS Information
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Teprenone Usage And Synthesis
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Description
Teprenone (geranylgeranylacetone) is an antiulcer agent whose synthesis was inspired by the gastric protecting properties of Coenzyme Q10. Teprenone is reported to act via enhancement of gastric mucosal glycoprotein secretion.
Chemical Properties
Yellow Oil
Originator
Eisai (Japan)
Uses
An anti-ulcerative. Geranylgeranylacetone can induce expression of HSP70, HSPB8, and HSPB1. Induction of HSP70 expression is protective against the development of various diseases, such as inflammatory bowel disease, hypoxic/ischemic brain injury and spinal and bulbar muscular atrophy (cytoprotective and anti-inflammatory effects). Reports indicate that GGA protects against NSAID-induced gastric and intestinal lesions by induction of HSP70 expression. Other studies have shown that GGA induces expression of HSPB8 and HSPB1 and reduces the formation of amyloid oligomers as well as insoluble aggregates in HSPB5 R120G TG mice.
Definition
ChEBI: A terpene ketone in which a (9E,13E)-geranylgernayl group is bonded to one of the alpha-methyls of acetone (it is a mixture of 5E- and 5Z-geoisomers in a 3:2 ratio).
Brand name
SELBEX
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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