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Postion:Product Catalog >API>Antibiotics>Penicillins drugs>Dicloxacillin sodium
Dicloxacillin sodium
  • Dicloxacillin sodium

Dicloxacillin sodium

Price $1
Package 1KG
Min. Order: 1KG
Supply Ability: 10000KGS
Update Time: 2020-01-03

Product Details

Product Name: Dicloxacillin sodium CAS No.: 13412-64-1
Min. Order: 1KG Purity: 99%
Supply Ability: 10000KGS Release date: 2020/01/03
Email:hanne@coreychem.com
wechat/whastapp:+8615670622393
hanne 858
Product Name:
Dicloxacillin sodium
Synonyms:
3-(2,6-DICHLOROPHENYL)-5-METHYL-4-ISOXAZOLYL PENICILLIN;DICLOXACILLIN SODIUM SALT HYDRATE VETRAN;DICLOXACILLIN SODIUM EPD(CRM STANDARD);DICLOXACILLIN SODIUM USP(CRM STANDARD);DICLOXACILLIN SODIUM WHO(CRM STANDARD);4-Thia-1-azabicyclo3.2.0heptane-2-carboxylic acid, 6-3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolylcarbonylamino-3,3-dimethyl-7-oxo-, monosodium salt, monohydrate, (2S,5R,6R)-;Dicloxacillin sodium;Sodium 7-[3-(2,6-dichlorophenyl)-5-methyl-oxazol-4-yl]carbonylamino-3,3-dimet hyl-6-oxo-2-thia-5-azabicyclo[3.2.0]heptane-4-carboxylate
CAS:
13412-64-1
MF:
C19H16Cl2N3NaO5S·H2O
MW:
510.32
EINECS:
603-794-2
Product Categories:
APIs;A - KAntibiotics;Antibacterial;Antibiotics A to;Antibiotics A-FAntibiotics;Chemical Structure Class;Interferes with Cell Wall SynthesisAntibiotics;Mechanism of Action;Penicillins and Cephalosporins (beta-Lactams);Spectrum of Activity;Peptide Synthesis/Antibiotics;Aromatics;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;Diclocil
Mol File:
13412-64-1.mol
Article illustration
 
Dicloxacillin sodium Chemical Properties
Melting point 
222-225°C
alpha 
D20 +127.2° (water)
storage temp. 
2-8°C
solubility 
H2O: soluble50mg/mL
form 
powder
color 
white to off-white
Water Solubility 
Soluble in water
BRN 
4778711
CAS DataBase Reference
13412-64-1(CAS DataBase Reference)
 
Safety Information
Hazard Codes 
Xn
Risk Statements 
36/37/38-42/43
Safety Statements 
22-26-36/37-45
WGK Germany 
2
RTECS 
XH8925000
HS Code 
29411099
Toxicity
LD50 in mice (g/kg): 0.9 i.v.; in rats (g/kg): 0.63 i.p.; >5 orally (Gloxhuber)
MSDS Information
 
 
Dicloxacillin sodium Usage And Synthesis
Brand Name(s) in US
Dynapen
Chemical Properties
White to off-white crystalline powder
Uses
A semi-synthetic antibiotic related to Penicillin. Antibacterial.
Uses
Antibacterial;Bacterial transpeptidase inhibitor
Brand name
Dynapen (Apothecon).
General Description
The substitution of chlorine atoms on both carbons orthoto the position of attachment of the phenyl ring to the isoxazolering is presumed to enhance further the stability ofthe oxacillin congener dicloxacillin sodium, [3-(2,6-dichlorophenyl)-5-methyl-4-isoxazolyl]penicillin sodiummonohydrate (Dynapen, Pathocil, Veracillin) and toproduce high plasma concentrations of it. Its medicinalproperties and use are similar to those of cloxacillinsodium. Progressive halogen substitution, however, alsoincreases the fraction bound to protein in the plasma, potentiallyreducing the concentration of free antibiotic inplasma and tissues. Its medicinal properties and use are thesame as those of cloxacillin sodium.
Veterinary Drugs and Treatments
The veterinary use of dicloxacillin has been primarily in the PO treatment of bone, skin, and other soft tissue infections in small animals when penicillinase-producing Staphylococcus species have been isolated. Because of its low oral bioavailability and short halflife, other drugs with good staph coverage are usually employed.

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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