CYCLOSPORIN D
| Price | $1 |
| Package | 1KG |
| Min. Order: | 1KG |
| Supply Ability: | 1ton |
| Update Time: | 2020-01-03 |
Product Details
| Product Name: CYCLOSPORIN D | CAS No.: 63775-96-2 |
| EC-No.: 200-258-5 | Min. Order: 1KG |
| Purity: 95-99% | Supply Ability: 1ton |
| Release date: 2020/01/03 | |
| contact: Flora@coreychem.com |
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CYCLOSPORIN D Basic information
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Product Name:
CYCLOSPORIN D
Synonyms:
Cyclosporine EP Impurity D;CYCLOSPORIN D;Val2-cyclosporine;(3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]-cyclo(L-Leu-L-Val-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-);(3R,4R)-3-Hydroxy-N-methyl-5-[(E)-1-propenyl]cyclo(L-Leu-L-Val-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-);Cyclo[L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-3-hydroxy-N,4-dimethyl-L-2-amino-6-octenoyl-L-valyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl];7-L-Valinecyclosporin A;Cyclosporine IMpurity-D
CAS:
63775-96-2
MF:
C63H111N11O12
MW:
1214.62
EINECS:
806-434-4
Product Categories:
ACTIVE PHARMACEUTICAL INGREDIENTS;Intermediates & Fine Chemicals;Anti-cancer&immunity;Peptides;Pharmaceuticals
Mol File:
63775-96-2.mol
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CYCLOSPORIN D Chemical Properties
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Melting point
148-1510C
alpha
D20 -245° (c = 0.52 in CHCl3); D20 -211° (c = 0.51 in methanol)
Boiling point
1294.7±65.0 °C(Predicted)
density
1.015±0.06 g/cm3(Predicted)
Fp
9 °C
storage temp.
-20°C Freezer
pka
13.22±0.70(Predicted)
form
Colorless to off-white crystalline solid.
InChIKey
YJDYDFNKCBANTM-QCWCSKBGSA-N
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Safety Information
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Hazard Codes
F,Xn,T
Risk Statements
11-20/21/22-36-39/23/24/25-23/24/25
Safety Statements
16-36/37-45-7
RIDADR
UN 1648 3 / PGII
WGK Germany
2
HS Code
29419090
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MSDS Information
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CYCLOSPORIN D Usage And Synthesis
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Chemical Properties
Colorless Crystalline Solid
Uses
A group of nonpolar cyclic oligopeptides with immunosupppressant activity.
Uses
Cyclosporin D is a minor analogue of the cyclosporin family which is only weakly immunologically active. Cyclosporin D is a potent inhibitor of tumour-promoting phorbol esters on mouse skin in vivo, and a potent inhibitor of calcium/calmodulin-dependent EF-2 phosphorylation in vitro.
Uses
Cyclosporin D is a minor analogue of the cyclosporin family which is only weakly immunologically active. Cyclosporin D is a potent inhibitor of tumor-promoting phorbol esters on mouse skin in vivo, and a potent inhibitor of calcium/calmodulin-dependent EF-2 phosphorylation in vitro.
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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China- Since: 2014-12-17
- Address: 702, Building 10, East District, National University Science and Technology Park, High tech Zone, Zh
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