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Postion:Product Catalog >Biochemical Engineering>Biochemical Reagents>Agonist Inhibitors>Motesanib
Motesanib
  • Motesanib
  • Motesanib
  • Motesanib
  • Motesanib

Motesanib

Price $1
Package 1g
Min. Order: 1g
Supply Ability: 100kgs
Update Time: 2020-01-03

Product Details

Product Name: Motesanib CAS No.: 453562-69-1
Min. Order: 1g Purity: 99%
Supply Ability: 100kgs Release date: 2020/01/03

Mary

 

Product Name:
Motesanib
Synonyms:
N-(3,3-diMethylindolin-6-yl){2-[(4-pyridylMethyl)-aMino](3-pyridyl)}-carboxaMide;3-PyridinecarboxaMide, N-(2,3-dihydro-3,3-diMethyl-1H-indol-6-yl)-2-[(4-pyridinylMethyl)aMino]-;Motesanib Base;AMG-706(Motesanib);Motesanib (AMG-706) Base);motesanib;N-(2,3-Dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-3-pyridinecarboxamide;N-(3,3-dimethylindolin-6-yl)-2-(pyridin-4-ylmethylamino)nicotinamide,AMG706
CAS:
453562-69-1
MF:
C22H23N5O
MW:
373.45
EINECS:
 
Product Categories:
Antineoplastic;Inhibitors;API
Mol File:
453562-69-1.mol
Article illustration
 
Motesanib Chemical Properties
Boiling point 
517.3±50.0 °C(Predicted)
density 
1.251
form 
White powder solid.
pka
11.75±0.40(Predicted)
 
Safety Information
MSDS Information
 
 
Motesanib Usage And Synthesis
Chemical Properties
Pale Yellow Solid
Uses
Motesanib Diphosphate (AMG-706) is a potent ATP-competitive inhibitor of VEGFR1/2/3, PDGFR, c-Kit and Ret with IC50 of 2 nM/3 nM/6 nM, 84 nM, 8 nM and 59 nM, respectively.
Uses
Motesanib is an oral angiogenesis inhibitor, demonstrates clinical efficacy in advanced thymoma.
 
Motesanib Preparation Products And Raw materials

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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