1-AZAKENPAULLONE
| Price | $1 |
| Package | 1KG |
| Min. Order: | 1KG |
| Supply Ability: | 1ton |
| Update Time: | 2020-01-05 |
Product Details
| Product Name: 1-AZAKENPAULLONE | CAS No.: 676596-65-9 |
| EC-No.: 200-258-5 | Min. Order: 1KG |
| Purity: 95--99% | Supply Ability: 1ton |
| Release date: 2020/01/05 | |
| contact: flora@coreychem.com |
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1-AZAKENPAULLONE Basic information
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Product Name:
1-AZAKENPAULLONE
Synonyms:
InSolution 1-Azakenpaullone - CAS 676596-65-9 - Calbiochem;1-AZAKENPAULLONE;9-Bromo-7,12-dihydropyrido[3',2':2,3]azepino[4,5-b]indol-6(5H)-one;Pyrido[3',2':2,3]azepino[4,5-b]indol-6(5H)-one, 9-broMo-7,12-dihydro-;1-Azakenpaullone 9-Bromo-7,12-dihydropyrido[3',2':2,3]azepino[4,5-b]indol-6(5H)-one;InSolution? 1-Azakenpaullone;1-Azakenpaullone - CAS 676596-65-9 - Calbiochem
CAS:
676596-65-9
MF:
C15H10BrN3O
MW:
0
EINECS:
Product Categories:
All Inhibitors;Inhibitors;-;Protein Kinase Inhibitors and Activators
Mol File:
676596-65-9.mol
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1-AZAKENPAULLONE Chemical Properties
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Melting point
>290°C (dec.)
Boiling point
648.8±50.0 °C(Predicted)
density
1.655±0.06 g/cm3(Predicted)
storage temp.
-20°C Freezer
solubility
DMSO: >10mg/mL
pka
13.36±0.20(Predicted)
form
Tan solid
color
gray-brown
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Safety Information
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WGK Germany
2
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MSDS Information
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1-AZAKENPAULLONE Usage And Synthesis
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Chemical Properties
Tan Solid
Uses
A selective inhibitor of glycogen synthase kinase-3β.
Enzyme inhibitor
This cell-permeable protein kinase inhibitor (FW = 328.17 g/mol; CAS 676596-65-9: Solubility: 66 mg/mL DMSO; <1 mg/mL H2O), also named 9-bromo-7,12-dihydro-pyrido[3,2’:2,3]azepino[4,5-b]indol-6(5H)-one, selectively and potently targets glycogen synthase kinase 3β, or GSK3β (IC50 = 18 nM) with 100x less inhibitory action against cyclin-dependent kinases (CDKs). 1-Azakenpaullone has become a gold standard for GSK3 inhibition.
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1-AZAKENPAULLONE Preparation Products And Raw materials
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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