8-Chloroquinoline
| Price | $230 |
| Package | 100g |
| Min. Order: | 1g |
| Supply Ability: | 500 Kg |
| Update Time: | 2024-02-19 |
Product Details
| Product Name: 8-Chloroquinoline | CAS No.: 611-33-6 |
| Min. Order: 1g | Purity: 98 |
| Supply Ability: 500 Kg | Release date: 2024/02/19 |
| 8-Chloroquinoline |
8-Chloroquinoline is an organochlorine compound that has anti-malarial, anti-parasitic, and anti-bacterial properties. It binds to the parasite's enzyme hemozoin synthase to inhibit the production of hemozoin. 8-Chloroquinoline also inhibits bacterial growth by binding to the enzyme DNA gyrase and prevents bacterial replication. The binding of 8-chloroquinoline to DNA gyrase inactivates it, thus preventing supercoiling of the bacterial DNA. This causes a structural change in the DNA helix that inhibits transcription and replication. 8-Chloroquinoline has been shown to be effective against Mycobacterium tuberculosis with minimal toxicity for liver cells.
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