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Postion:Product Catalog >API>Circulatory system drugs>Antihypertensive drugs>Cilazapril (monohydrate)
Cilazapril (monohydrate)
  • Cilazapril (monohydrate)

Cilazapril (monohydrate)

Price $1
Package 1g
Min. Order: 1g
Supply Ability: 1ton
Update Time: 2020-01-13

Product Details

Product Name: Cilazapril (monohydrate) CAS No.: 92077-78-6
EC-No.: 200-258-5 Min. Order: 1g
Purity: 95-99% Supply Ability: 1ton
Release date: 2020/01/13
contact: Mary@coreychem.com
Common Name
Cilazapril (monohydrate)
CAS Number
92077-78-6
Molecular Weight
435.51400
Density
N/A
Boiling Point
598.1ºC at 760mmHg
Molecular Formula
C22H33N3O6
Melting Point
98° (dec)
MSDS
N/A
Flash Point
315.5ºC

 Use of Cilazapril (monohydrate)

 
Cilazapril Monohydrate is a angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure.Target: ACECilazapril is a new nonthiol group containing angiotensin converting enzyme (ACE) inhibitor. Cilazapril has been investigated in more than 4000 patients with all degrees of hypertension, as well as in the special patient groups such as the elderly, renally impaired, and patients with concomitant diseases, such as congestive cardiac failure or chronic obstructive pulmonary disease [1]. Cilazapril is a very potent and highly effective converting enzyme inhibitor. Doses well below 5 mg/day will probably suffice for therapeutic efficacy [2].

 Names

Name
cilazapril
Synonym
More Synonyms

 Cilazapril (monohydrate) Biological Activity

Description
Cilazapril Monohydrate is a angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and congestive heart failure.Target: ACECilazapril is a new nonthiol group containing angiotensin converting enzyme (ACE) inhibitor. Cilazapril has been investigated in more than 4000 patients with all degrees of hypertension, as well as in the special patient groups such as the elderly, renally impaired, and patients with concomitant diseases, such as congestive cardiac failure or chronic obstructive pulmonary disease [1]. Cilazapril is a very potent and highly effective converting enzyme inhibitor. Doses well below 5 mg/day will probably suffice for therapeutic efficacy [2].
Related Catalog
Signaling Pathways >> Metabolic Enzyme/Protease >> Angiotensin-converting Enzyme (ACE)
Research Areas >> Cardiovascular Disease
References

[1]. Szucs, T., Cilazapril. A review. Drugs, 1991. 41 Suppl 1: p. 18-24.

[2]. Nussberger, J., et al., Repeated administration of the converting enzyme inhibitor cilazapril to normal volunteers. J Cardiovasc Pharmacol, 1987. 9(1): p. 39-44.

 Chemical & Physical Properties

Boiling Point
598.1ºC at 760mmHg
Melting Point
98° (dec)
Molecular Formula
C22H33N3O6
Molecular Weight
435.51400
Flash Point
315.5ºC
Exact Mass
435.23700
PSA
108.41000
LogP
1.79790

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UR6113250
CHEMICAL NAME :
6H-Pyridazino(1,2-a)(1,2)diazepine-1-carboxylic acid, octahydro-9-((1-(ethoxycarbonyl)-3- phenylpropyl)amino)-10-oxo-, hydrate, (1S-(1-alpha,9-alpha(R*)))-
CAS REGISTRY NUMBER :
92077-78-6
LAST UPDATED :
199706
DATA ITEMS CITED :
12
MOLECULAR FORMULA :

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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