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Postion:Product Catalog >Spirapril hydrochloride
Spirapril hydrochloride
  • Spirapril hydrochloride
  • Spirapril hydrochloride
  • Spirapril hydrochloride

Spirapril hydrochloride

Price $1
Package 1KG
Min. Order: 1KG
Supply Ability: 100kg
Update Time: 2020-01-15

Product Details

Product Name: Spirapril hydrochloride CAS No.: 94841-17-5
Min. Order: 1KG Purity: 99.0%
Supply Ability: 100kg Release date: 2020/01/15
Spirapril hydrochloride Basic information
Product Name:
Spirapril hydrochloride
Synonyms:
Renormax;Renpress;Sandopril;TI 211-950;1,4-Dithia-7-azaspiro(4.4)nonane-8-carboxylic acid, 7-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-, monohydrochloride, (8S-(7(R*(R*)),8R*))-;Spirapril HCl;Unii-occ25lm897;Spirapril hydrochloride
CAS:
94841-17-5
MF:
C22H30N2O5S2.HCl
MW:
503.07
EINECS:
 
Product Categories:
Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds;API
Mol File:
94841-17-5.mol
Article illustration
 
Spirapril hydrochloride Chemical Properties
Melting point 
192-1940C (dec.)
alpha 
D26 -11.2° (c = 0.4 in ethanol)
storage temp. 
-20°C Freezer
solubility 
Very slightly soluble in water, soluble in methanol, slightly soluble in acetonitrile, practically insoluble in methylene chloride.
 
Safety Information
MSDS Information
 
 
Spirapril hydrochloride Usage And Synthesis
Description
Spirapril hydrochloride is a new ACE inhibitor introduced in Finland for the treatment of hypertension. Spirapril is orally active and rapidly absorbed and converted to the active diacid spiraprilat which produces a reduction in blood pressure similar to that seen with enalapril and captopril. Spirapril has been reported to be well tolerated and exhibits an apparently lower incidence of cough compared with other ACE inhibitors. The elimination of spirapril occurs via both renal and hepatic routes so that no dosage adjustment is required for patients with renal impairment. In patients with severe congestive heart failure, spirapril has demonstrated beneficial hemodynamic effects with a duration of action >24 hours.
Chemical Properties
White Solid
Originator
Schering-Plough (U.S.A.)
Uses
Angiotensin-converting enzyme (ACE) inhibior. Antihypertensive
Brand name
Renormax (Schering);Renpress.

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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