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Postion:Product Catalog >Biochemical Engineering>Inhibitors>Metabolism>PPAR agonists>Pioglitazone
Pioglitazone
  • Pioglitazone

Pioglitazone

Price $7
Package 1KG
Min. Order: 1KG
Supply Ability: 100KG
Update Time: 2020-02-13

Product Details

Product Name: Pioglitazone CAS No.: 111025-46-8
Min. Order: 1KG Purity: 99%
Supply Ability: 100KG Release date: 2020/02/13
Name : Judy Liang 607
 
 
 
Product Name: Pioglitazone
Synonyms: 5-[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]benzyl]thiazolidine-2,4-dione;Pioglitazone (Actos);2,4-Thiazolidinedione,5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]Methyl]-;Pioglitazone 5-[[4-[2-(5-Ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione;5-[4-[2-(5-ETHYL-2-PYRIDINYL)ETHOXY]PHENYL]METHYL-2,4-THIAZOLIDINEDIONE;5-(4-[2-(5-ETHYL-PYRIDIN-2-YL)-ETHOXY]-BENZYL)-THIAZOLIDINE-2,4-DIONE;Pioglitazone;PIOGLITAZONE HCL(5-[[4-[2-(5-ETHYLPYRIDIN-2-YL)ETHOXY]PHENYL]METHYL]THIAZOLIDINE-2,4-DIONE, HCL)
CAS: 111025-46-8
MF: C19H20N2O3S
MW: 356.44
EINECS: 601-029-7
Product Categories: APIS;LESCOL
Mol File: 111025-46-8.mol
Pioglitazone Structure
Pioglitazone Chemical Properties
Melting point 183-184 C
Boiling point 575.4±45.0 °C(Predicted)
density 1.260±0.06 g/cm3(Predicted)
form White to off-white solid.
pka 6.35±0.50(Predicted)
Safety Information
Hazard Codes F,C
Risk Statements 11-34
Safety Statements 16-26-36/37/39-45
Hazardous Substances Data 111025-46-8(Hazardous Substances Data)
MSDS Information
Provider Language
Pioglitazone English
Pioglitazone Usage And Synthesis
Uses antihyperlipidemic, HMGCoA reductase inhibitor
Definition ChEBI: A member of the class of thiazolidenediones that is 1,3-thiazolidine-2,4-dione substituted by a benzyl group at position 5 which in turn is substituted by a 2-(5-ethylpyridin-2-yl)ethoxy group at position 4 of the phenyl ring. It exhibits hypoglycemic acti ity.
Indications Pioglitazone is approved for use as monotherapy and in conjunction with metformin, sulfonylureas, and insulin. It is taken once a day with or without food. Though pioglitazone may also cause a small increase in low-density lipoprotein concentrations, there is usually a modest decrease in triglyceride levels, but it unclear whether this has any clinical significance or persists in the long term.
Brand name Actos (Takeda).
General Description Pioglitazone, (±)-5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione (Actos),is an odorless, white, crystalline powder that must be convertedto a salt such as its hydrochloride before it will haveany water solubility. Although the molecule contains one chiralcenter, the compound is used as the racemic mixture. Thisis primarily a result of the in vivo interconversion of the twoenantiomers. Thus, there are no differences in the pharmacologicalactivity of the two enantiomers.

Company Profile Introduction

Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals. Mainly deals in the sales of: Pharmaceutical intermediates OLED intermediates: Pharmaceutical intermediates; OLED intermediates;

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