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Postion:Product Catalog >84-B10
84-B10
  • 84-B10

84-B10 NEW

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Package 1removed
Supply Ability: 10g
Update Time: 2026-05-11

Product Details

Product Name: 84-B10 CAS No.: 698346-43-9
Supply Ability: 10g Release date: 2026/05/11

Product Introduction

Bioactivity

Name84-B10
Description84-B10 protects against cisplatin-induced acute kidney injury, reversing lipid peroxidation accumulation and downregulation of key ferroptosis inhibitors, inhibiting mitochondrial damage and mtROS production, and restoring superoxide dismutase to reduce cisplatin-induced kidney damage.
In vitro84-B10 (10-100 μM,2 h) inhibited cisplatin induced iron death in renal tubular epithelial cells in a dose-dependent manner. Treatment with 84-B10 (40 μM, 2 hours) restored cisplatin induced mitochondrial structural damage and dysfunction. 84-B10 (40 μM, 2 hours) mitigated MTROS-induced oxidative stress in cisplatin-induced AKI. 84-B10 (40 μM, 2 hours) alleviates cisplatin induced epithelial cell damage by eliminating mtROS and restoring mitochondrial homeostasis [1].
In vivo84-B10 plays a protective role in cisplatin induced acute kidney injury, but has no tumor-promoting effect. [1]
StorageShipping with blue ice.
Solubility Information10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (4.22 mM), Sonication is recommended.
H2O : < 0.1 mg/mL (insoluble)
DMSO : 80 mg/mL (168.98 mM), Sonication is recommended.
Inhibitors RelatedRosiglitazone | Hemin | L-Glutamic acid | Sorafenib | Curcumin | Gallic Acid Monohydrate | L-Cystine | L-Glutamine | (-)-Epigallocatechin Gallate | Coenzyme Q10 | Baicalein | Sodium Molybdate
Related Compound LibrariesFerroptosis Compound Library | Bioactive Compound Library | Bioactive Compounds Library Max

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

4YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, USA
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