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Postion:Product Catalog >Chemical Reagents>Organic reagents>Guanidine salt>Guanidine hydrochloride
Guanidine hydrochloride
  • Guanidine hydrochloride
  • Guanidine hydrochloride
  • Guanidine hydrochloride
  • Guanidine hydrochloride
  • Guanidine hydrochloride

Guanidine hydrochloride NEW

Price $2000
Package 1T
Min. Order: 1T
Supply Ability: 20tons
Update Time: 2025-06-20

Product Details

Product Name: Guanidine hydrochloride CAS No.: 50-01-1
EC-No.: 200-002-3 Min. Order: 1T
Purity: 99% Supply Ability: 20tons
Release date: 2025/06/20

Guanidinium chloride or guanidine hydrochloride, usually abbreviated GdmCl and sometimes GndCl or GuHCl, is the hydrochloride salt of guanidine.

Character

Melting Point180-185 °C
Density1.18 g/mL at 25 °C
Refractive Indexn20/D 1.465
Condition Storage
room temp
SolubilitySolubility in water 6 M, transparent, colorless
PH4.5-5.5 (100g/l, H2O, 20℃)
Water Solubility
2280 g/L (20 oC)

Preparation method: 

Guanidine hydrochloride preparation method, with the following process: 

a, melting, the weight ratio of 1∶1.27 dicyandiamide and ammonium chloride into the reactor, melting reaction at 170 ~ 230℃, guanidine hydrochloride crude product; 

b, dissolve, at room temperature, dissolve guanidine hydrochloride in water at a ratio of 1 to 1, and add ammonium salt alkali to the solution according to the content of ammonium salt in guanidine hydrochloride; 

c, filtration, the raw materials and reaction by-products are removed by filtration method; 

d, dehydration, the filtered mother liquor at high temperature dehydration; 

e, crystallization, supersaturated solution cooling, concentrated crystallization, to obtain high-purity guanidine hydrochloride. 

f, the guanidine hydrochloride after step e is added into the dicyandiamide into the reactor, the melting reaction is carried out at 170 ~ 230℃ for 3 ~ 4h, and then through steps b, c, d, e, to obtain higher purity guanidine hydrochloride, and this step can be repeated several times according to needs. g. The guanidine hydrochloride after step e is then passed through steps b, c, d and e, where the ratio of step b to water is 1.5∶1 to obtain higher purity guanidine hydrochloride, and this step can be repeated several times as needed.

Application

It is often used for denaturing proteins and refolding after denaturing proteins.

As an intermediate of medicine, pesticide, dye and other organic synthesis, it is an important raw material for manufacturing sulfanilamide drugs and folic acid, and can also be used as an antistatic agent for synthetic fiber. It is an important raw material for producing sulfadiazine, sulfadiazine, sulfadiazine and folic acid.

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Company Profile Introduction

Hebei Yanxi Chemical Co. LTD., mainly produce the Carbomer940/980/u21 and lead acetate and lead oxide, lead stearate, lead salt, at the same time operating organic intermediates, surfactants, Food additive,inorganic salt, plant extracts, cosmetics raw material, etc., through long-term development, hebei said bush chemical co., LTD. In hebei province has become a collection of r &d, production, sales in the integration of high-tech enterprises.

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