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Postion:Product Catalog >API>Nervous system drugs>Antidepressants, Antimanics drugs>Amitriptyline
Amitriptyline
  • Amitriptyline

Amitriptyline NEW

Price $39 $62 $91
Package 10mg 25mg 50mg
Supply Ability: 10g
Update Time: 2026-04-22

Product Details

Product Name: Amitriptyline CAS No.: 50-48-6
Purity: 99.45% Supply Ability: 10g
Release date: 2026/04/22

Product Introduction

Bioactivity

NameAmitriptyline
DescriptionAmitriptyline (MK-230, N-750, Ro41575) is a tricyclic antidepressant (TCA) with analgesic properties. Amitriptyline is widely used to treat depression and neuropathic pain.
In vitroAmitriptyline inhibits both serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki of 3.45 nM and 13.3 nM, respectively. Amitriptyline is also an inhibitor of histamine receptor H1, histamine receptor H4, 5-HT2 and sigma 1 receptor with Ki of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively.
StoragePure form: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationH2O : 9.7 mg/mL (34.97 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (7.21 mM), Sonication is recommended.
Keywordsσ1 | Sigmareceptor | Sigma receptor | SERT | norepinephrine transporter (NET) | HistamineReceptor | Histamine Receptor | H4 receptor | H1 receptor | Amitriptyline | 5HTReceptor | 5-HT2 | 5HT Receptor
Inhibitors RelatedPhenytoin sodium | Alverine citrate | Meclizine dihydrochloride | Urethane | Famotidine | 1,8-Cineole | Adenine | Valproic Acid | Sodium butanoate | N,N-Dicyclohexylcarbodiimide | Alginic acid | Cinchonidine
Related Compound LibrariesBioactive Compound Library | Pain-Related Compound Library | Anti-Neurodegenerative Disease Compound Library | Membrane Protein-targeted Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | FDA-Approved Drug Library | Anti-Cancer Approved Drug Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Drug Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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