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Postion:Product Catalog >Biochemical Engineering>Inhibitors>Metabolism>PDE inhibitors>Pimobendan
Pimobendan
  • Pimobendan

Pimobendan NEW

Price Get Latest Price
Package 1KG
Min. Order: 1KG
Supply Ability: 1000kg
Update Time: 2026-06-03

Product Details

Product Name: Pimobendan CAS No.: 74150-27-9
EC-No.: 640-420-7 Min. Order: 1KG
Purity: 99% Supply Ability: 1000kg
Release date: 2026/06/03

Pimobendan is a specialized veterinary medication used almost exclusively in dogs for the management of congestive heart failure (CHF) caused by specific cardiac conditions. Its unique dual-action mechanism makes it a cornerstone therapy in veterinary cardiology. Here's a detailed breakdown of its applications:


1. Primary Application: Canine Heart Failure Management

Target Conditions:

  • Myxomatous Mitral Valve Disease (MMVD):

    • The most common indication. Used for CHF secondary to degenerative mitral valve disease (Stage C and D per ACVIM guidelines).

  • Dilated Cardiomyopathy (DCM):

    • Especially in breeds like Doberman Pinschers, Boxers, and Great Danes.

Mechanism of Action:

Pimobendan works via two synergistic pathways:

  1. Calcium Sensitization:

    • Enhances cardiac contractility by making troponin C more sensitive to calcium (improves systolic function without increasing oxygen demand).

  2. Phosphodiesterase III (PDE3) Inhibition:

    • Causes vasodilation (reduces afterload) and mild vasodilation (reduces preload), easing the heart's workload.

Key Benefits:

  • Prolongs survival time in dogs with CHF.

  • ? Improves quality of life (reduces coughing, exercise intolerance, breathing difficulty).

  • ? Delays onset of CHF in pre-clinical dogs with cardiomegaly (Stage B2).



Company Profile Introduction

Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals in distributing the products of our own company and affiliated enterprises, are the members of Hubei E-commerce Chamber.

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