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Postion:Product Catalog >A-3 hydrochloride
A-3 hydrochloride
  • A-3 hydrochloride

A-3 hydrochloride NEW

Price $51 $79 $156
Package 5mg 10mg 25mg
Supply Ability: 10g
Update Time: 2026-07-15

Product Details

Product Name: A-3 hydrochloride CAS No.: 78957-85-4
Purity: 99.79% Supply Ability: 10g
Release date: 2026/07/15

Product Introduction

Bioactivity

NameA-3 hydrochloride
DescriptionA-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. It inhibits PKC and casein kinase I with Ki values of 47 μM and 80 μM, respectively[1], and also inhibits PKA (Ki=4.3 μM), casein kinase II (Ki=5.1 μM), and myosin light chain kinase (MLCK) (Ki=7.4 μM).
In vitroA-3 hydrochloride competitively inhibits MLC-kinase with respect to ATP, with a Ki value of 7.4 μM. It also competitively inhibits cAMP-dependent protein kinase, cGMP-dependent protein kinase, protein kinase C, casein kinase I, and casein kinase II with ATP, exhibiting Ki values of 4.3 μM, 3.8 μM, 47 μM, 80 μM, and 5.1 μM, respectively[1].
StorageKeep away from moisture, Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+40% PEG300+5% Tween 80+45% Saline : 4 mg/mL (12.45 mM), Sonication is recommended.
DMSO : 125 mg/mL (389.14 mM), Sonication is recommended.
KeywordsProtein kinase C | Protein kinase A | PKC | PKA | MLC-kinase | kinase | inhibitor | inhibit | CK2 | CK1 | CaseinKinase | Casein Kinase | casein | cAMP | CaMK | Calmodulin-dependent protein kinases | Calmodulin-dependent kinases | calmodulin | A-3 Hydrochloride | A3 Hydrochloride | A-3 | A 3 hydrochloride | A 3
Inhibitors RelatedUndecane | Trifluoperazine dihydrochloride | Rhamnose monohydrate | α-Vitamin E | Casein | Acefylline | Dibucaine | Miltefosine | CaMKP Inhibitor | D-Mannitol | (-)-Limonene | Isovaleric acid
Related Compound LibrariesReprogramming Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Tyrosine Kinase Inhibitor Library | Kinase Inhibitor Library | Inhibitor Library | Stem Cell Differentiation Compound Library | NO PAINS Compound Library | Bioactive Compounds Library Max | Cytoskeletal Signaling Pathway Compound Library | Anti-Cancer Compound Library | TGF-beta/Smad Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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