A-3 hydrochloride NEW
| Price | $51 | $79 | $156 |
| Package | 5mg | 10mg | 25mg |
| Supply Ability: | 10g |
| Update Time: | 2026-05-26 |
Product Details
| Product Name: A-3 hydrochloride | CAS No.: 78957-85-4 |
| Purity: 99.79% | Supply Ability: 10g |
| Release date: 2026/05/26 |
Product Introduction
Bioactivity
| Name | A-3 hydrochloride |
| Description | A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. It inhibits PKC and casein kinase I with Ki values of 47 μM and 80 μM, respectively[1], and also inhibits PKA (Ki=4.3 μM), casein kinase II (Ki=5.1 μM), and myosin light chain kinase (MLCK) (Ki=7.4 μM). |
| In vitro | A-3 hydrochloride competitively inhibits MLC-kinase with respect to ATP, with a Ki value of 7.4 μM. It also competitively inhibits cAMP-dependent protein kinase, cGMP-dependent protein kinase, protein kinase C, casein kinase I, and casein kinase II with ATP, exhibiting Ki values of 4.3 μM, 3.8 μM, 47 μM, 80 μM, and 5.1 μM, respectively[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 4 mg/mL (12.45 mM), Sonication is recommended. DMSO : 125 mg/mL (389.14 mM), Sonication is recommended. |
| Keywords | Protein kinase C | Protein kinase A | PKC | PKA | MLC-kinase | kinase | inhibitor | inhibit | CK2 | CK1 | CaseinKinase | Casein Kinase | casein | cAMP | CaMK | Calmodulin-dependent protein kinases | Calmodulin-dependent kinases | calmodulin | A-3 Hydrochloride | A3 Hydrochloride | A-3 | A 3 hydrochloride | A 3 |
| Inhibitors Related | Undecane | Trifluoperazine dihydrochloride | Rhamnose monohydrate | α-Vitamin E | Casein | Acefylline | Dibucaine | Miltefosine | CaMKP Inhibitor | D-Mannitol | (-)-Limonene | Isovaleric acid |
| Related Compound Libraries | Reprogramming Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Tyrosine Kinase Inhibitor Library | Kinase Inhibitor Library | Inhibitor Library | Stem Cell Differentiation Compound Library | NO PAINS Compound Library | Bioactive Compounds Library Max | Cytoskeletal Signaling Pathway Compound Library | Anti-Cancer Compound Library | TGF-beta/Smad Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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