Abemaciclib Impurity 13

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E-mail: anna@molcoo.com

• English Version

• Product Information:
  Product Code: A066013
  English Name: Abemaciclib Impurity 13
  English Alias: (6-((5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-yl)amino)pyridin-3-yl)methanol
  CAS No.: 1648707-16-7
  Molecular Formula: C21H20F2N6O
  Molecular Weight: 410.42
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• Product Advantages:
  This product has high purity, which can accurately meet the strict requirements for impurity reference substances in abemaciclib drug quality control and related research. It has good chemical stability and can maintain stable physical and chemical properties for a long time under standardized storage conditions, providing a strong guarantee for the repeatability and accuracy of experiments. Strict quality control is implemented during the production process, with small differences between batches, which can effectively reduce experimental errors and provide a reliable material basis for scientific research and production work.
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• Product Applications:
  It is mainly used in the quality control field of abemaciclib, serving as an impurity reference substance to detect the content of this impurity in abemaciclib raw materials and various preparations, ensuring that the drug quality meets relevant standards. Moreover, in the research and development process of abemaciclib, it can be used to explore the formation mechanism of this impurity and its impact on drug efficacy and safety, providing important data references for optimizing production processes and improving drug quality.
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• Background Description:
  Abemaciclib is a cyclin-dependent kinase (CDK4/6) inhibitor, mainly used in the treatment of hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced or metastatic breast cancer. It works by inhibiting CDK4/6 enzyme activity to prevent cancer cell proliferation. During its synthesis, storage and preparation processes, various impurities may be generated due to factors such as incomplete reactions, raw material impurities or degradation, and Abemaciclib Impurity 13 is one of them. If the content of these impurities exceeds the standard, it may affect the efficacy and stability of the drug, and even bring potential safety risks. Therefore, accurate detection and strict control of them are of great significance.
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• Research Status:
  At present, research on Abemaciclib Impurity 13 mainly focuses on the development and optimization of detection methods, such as high-performance liquid chromatography (HPLC) and liquid chromatography-mass spectrometry (LC-MS), to improve the sensitivity and accuracy of detection. At the same time, studies on the source, stability of this impurity and its interaction with the main component of abemaciclib are also gradually being carried out, providing a scientific basis for improving the quality standards and safety evaluation system of abemaciclib.

We can also customize related analogues and modified peptides including HPLC, MS, 1H-NMR, MS, HPLC, IR, UV, COA, MSDS.
This product is intended for laboratory use only!

WhatsAPP: +86 17386083646
E-mail: anna@molcoo.com