Product Details
| Product Name: Abeprazan hydrochloride | CAS No.: 1902954-87-3 |
| Min. Order: 1kg | Purity: 99% |
| Supply Ability: 100kg | Release date: 2026/04/17 |
| Lead time: in stock | Packaging: bag/bottle/drum//IBC, as request |
| Delivery: By sea, by air, by express | Origin: Manufacturer, advantage products |
| COA, MSDS: Available, contact us for details | Contact: Tina |
PRODUCT INFORMATION
| Name | Abeprazan hydrochloride |
|---|
| Description | Abeprazan hydrochloride (DWP14012 hydrochloride) is a potassium-competitive acid blocker. Abeprazan hydrochloride inhibits H+, K+- ATPase by reversible potassium-competitive ionic binding with no acid activation required. Abeprazan hydrochloride is developed as a potential alternative to proton pump inhibitor for the treatment of acid-related diseases[1]. |
|---|---|
| Related Catalog | Research Areas >> Metabolic Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Proton Pump |
| In Vitro | The mechanism of action of Abeprazan hydrochloride is reversibly binding to H+, K+‐ATPase, and, unlike that of PPIs, does not require acidic environment for drug activation[1]. |
| In Vivo | Abeprazan hydrochloride (DWP14012 hydrochloride) inhibits acid secretion in a dose-dependent manner and the inhibition of gastric acid secretion is equal to or greater than that of vonoprazan, a previously approved P-CAB, in various in vivo studies using pylorus-ligated rats, lumen-perfused rat models and heidenhain pouch dog models[1]. |
| References | [1]. Sunwoo J, et al. Safety, tolerability, pharmacodynamics and pharmacokinetics of DWP14012, a novel potassium-competitive acid blocker, in healthy male subjects. Aliment Pharmacol Ther. 2018 Jul;48(2):206-218. |
| Molecular Formula | C19H18ClF3N2O3S |
|---|---|
| Molecular Weight | 446.87 |
Company Profile
Our company is a high-tech enterprise specializing in chemical raw materials such as electronic materials, optoelectronic materials, semiconductor materials, UV monomers, silane catalysts, cosmetic raw materials, etc. The company integrates research and development, production, customized synthesis, and sales, and is committed to providing customers with high-quality chemical product solutions.
Our Company
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Rich experience
Our products have been exported to many countries, including Germany, Spain, the United Kingdom, the United States, Australia, the Middle East, Asia, and more. We have received highly positive feedback from our clients and have established long-term friendly cooperative relationships with them.
Excellent quality, purity, and competitive price
Excellent quality is one of the cornerstones of our success. We welcome ordering samples for quality testing.
Safe and fast delivery
We will arrange shipment of spot products as soon as we receive payment.
Customized products are determined based on the synthesis time of different products.
Excellent pre-sales and after-sales service
Pre sales:
We are committed to providing the most favorable quotes and detailed information about our products and company.
after-sale service:
We assist buyers in customs clearance by providing necessary documents and information.
If there is any dispute over product quality, we are committed to providing the best solution.
? Packaging:
1kg/bag, 25kg/drum, 50kg/drum, 180kg/drum, 200kg/drum, 1T/bag/drum, standard export packaging or packaging required by customers
? Shipping
? Delivery:
Within 7 days after receiving your payment
Contact information
For more details, pls contact us freely.
Contact name: Tina
Email address: Tina@fdachem.com
Mob: 86 13213167925
WhatsApp/Skype/Wechat/LINE: 86 15225627621
Company Profile Introduction
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