Acebutolol hydrochloride NEW
| Price | $42 | $48 | $61 |
| Package | 50mg | 100mg | 200mg |
| Supply Ability: | 10g |
| Update Time: | 2026-06-02 |
Product Details
| Product Name: Acebutolol hydrochloride | CAS No.: 34381-68-5 |
| Purity: 99.92% | Supply Ability: 10g |
| Release date: 2026/06/02 |
Product Introduction
Bioactivity
| Name | Acebutolol hydrochloride |
| Description | Acebutolol hydrochloride (Acebutolol HCl) acts as a cardioselective beta-adrenergic antagonist with little effect on bronchial receptors and has intrinsic sympathomimetic properties. Acebutolol hydrochloride is the hydrochloride salt form of acebutolol, a synthetic butyranilide derivative with hypotensive and antiarrhythmic activity. Having stabilizing and quinidine-like effects on cardiac rhythm, Acebutolol hydrochloride is used in ventricular arrhythmias. Other indications include hypertension, alone or in combinations with other agents. |
| In vitro | In J774 macrophages, Acebutolol (not bound to LDL) inhibited intracellular cholesteryl ester accumulation more strongly than oxenolol (bound to LDL) and Alprenolol.Acebutolol inhibited the uptake of NA by rat brain P2 fragments (IC50: 0.25 mM).CYP (125I-labeled) binds to human adipocyte membranes. The binding of CYP (125I-labeled) to human adipocyte membranes was inhibited by Acebutolol, and it replaced all specifically bound radioligands. 1 μM isoproterenol-induced lipolysis was completely inhibited by Acebutolol. |
| In vivo | In J774 macrophages, Acebutolol (not bound to LDL) inhibited intracellular cholesteryl ester accumulation more strongly than oxenolol (bound to LDL) and Alprenolol.Acebutolol inhibited the uptake of NA by rat brain P2 fragments (IC50: 0.25 mM).CYP (125I-labeled) binds to human adipocyte membranes. The binding of CYP (125I-labeled) to human adipocyte membranes was inhibited by Acebutolol, and it replaced all specifically bound radioligands. 1 μM isoproterenol-induced lipolysis was completely inhibited by Acebutolol. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | Ethanol : 70 mg/mL (187.72 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (5.36 mM), Sonication is recommended. H2O : 69 mg/mL (185.04 mM), Sonication is recommended. DMSO : 250 mg/mL (670.44 mM), Sonication is recommended. 10% DMSO+90% Saline : 10 mg/mL (26.82 mM), Solution. |
| Keywords | β-adrenergic receptor | Inhibitor | inhibit | Beta Receptor | AdrenergicReceptor | Adrenergic Receptor | Acebutolol Hydrochloride | Acebutolol |
| Inhibitors Related | Trifluoperazine dihydrochloride | Mirtazapine | Octopamine hydrochloride | Gemfibrozil | Buflomedil hydrochloride | Dexmedetomidine hydrochloride | Isoprenaline hydrochloride | D-Mannitol | Mianserin hydrochloride | Trazodone hydrochloride | Atenolol | Doxepin hydrochloride |
| Related Compound Libraries | FDA-Approved & Pharmacopeia Drug Library | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Membrane Protein-targeted Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | FDA-Approved Drug Library | Anti-Cancer Approved Drug Library | Bioactive Compounds Library Max | GPCR Compound Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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