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Postion:Product Catalog >API>Urinary System Drugs>Other Urinary System Drugs>Acetohydroxamic acid
Acetohydroxamic acid
  • Acetohydroxamic acid

Acetohydroxamic acid NEW

Price Get Latest Price
Package 1KG
Min. Order: 1KG
Supply Ability: 2000KG
Update Time: 2026-06-03

Product Details

Product Name: Acetohydroxamic acid CAS No.: 546-88-3
EC-No.: 208-913-8 Min. Order: 1KG
Purity: 98% Supply Ability: 2000KG
Release date: 2026/06/03
Acetohydroxamic acid (AHA, CAS 546-88-3) is a synthetic organic compound with a hydroxamic acid functional group (-CONHOH), and its applications are mainly focused on clinical medicine and industrial fields, with a small number of uses in scientific research. The details are as follows:

1. Clinical Medical Applications (Core Use)

The primary clinical role of acetohydroxamic acid is as a urease inhibitor, which is the key mechanism for its therapeutic effects.
  • Treatment of urinary tract infections (UTIs) caused by urease-producing bacteria

    Urease-producing bacteria (e.g., ProteusKlebsiellaPseudomonas) can decompose urea in urine into ammonia, leading to alkalization of urine and the formation of magnesium ammonium phosphate (struvite) and calcium phosphate stones (urolithiasis).

    Acetohydroxamic acid inhibits bacterial urease activity, reduces ammonia production, lowers urine pH, and prevents the formation and growth of urinary stones. It is often used as an adjunctive drug combined with antibiotics to treat recurrent UTIs associated with struvite stones, especially for patients who cannot undergo surgical stone removal.

  • Adjunctive treatment of Helicobacter pylori (H. pylori) infections

    H. pylori produces urease to neutralize gastric acid and survive in the acidic gastric environment. Although acetohydroxamic acid is not a first-line drug for H. pylori eradication, it can be used as an alternative adjunct in combination with proton pump inhibitors (PPIs) and antibiotics for patients with drug-resistant H. pylori infections, to enhance the eradication effect by inhibiting urease.

2. Industrial Applications

  • Metal chelating agent

    The hydroxamic acid group of acetohydroxamic acid has a strong chelating ability with metal ions (e.g., Fe3?, Cu2?, Ni2?). It is used in industrial water treatment to prevent metal ion-induced scaling in pipelines and equipment; it can also be applied in mineral processing as a flotation collector for certain metal ores (e.g., wolframite, tantalite).

  • Corrosion inhibitor

    It can form a stable chelate film on the surface of metal equipment, especially for iron and steel products, to reduce corrosion caused by acidic or alkaline media in industrial environments.

3. Scientific Research Applications

  • Enzyme inhibition research

    As a classic urease inhibitor, it is widely used in biochemical experiments to study the structure and function of urease, and to screen and develop new urease inhibitors with higher efficiency and lower toxicity.

  • Biological mechanism studies

    It is used in cell and molecular biology research to explore the role of urease in bacterial pathogenicity, and to verify the relationship between urease activity and disease progression (e.g., urinary stone formation, gastric mucosal damage).


Company Profile Introduction

Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals in distributing the products of our own company and affiliated enterprises, are the members of Hubei E-commerce Chamber.

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  • Since: 2006-04-03
  • Address: Room 2015, No.2 Building Kaixin Mansion
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